2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) - Cas: 1044871-04-6
Lambar Catalog | XD90961 |
Sunan samfur | 2- (3,5-Dimethyl-4- (2- (pyrrolidin-1-yl) ethoxy) phenyl) -5,7-dimethoxyquinazolin-4 (3H) -daya |
CAS | 1044871-04-6 |
Tsarin kwayoyin halitta | Saukewa: C24H29N3O4 |
Nauyin Kwayoyin Halitta | 423.5 |
Bayanin Ajiya | |
Harmonized Tariff Code |
Ƙayyadaddun samfur
Bayyanar | |
Assay | |
Bwurin mai | 612.6 ± 65.0 °C (An annabta) |
Yawan yawa | 1.25± 0.1 g/cm3 (An annabta) |
Matsakaicin acidity | (pKa) 9.54± 0.20 (An annabta) |
RVX-297 mai ƙarfi ne mai ƙarfi, mai hanawa BET na baka mai zaɓi don BD2.IC50s na RVX-297 don BRD2 (BD2), BRD3 (BD2), da BRD4 (BD2) sun kasance 0.08, 0.05, da 0.02 μM, bi da bi.RVX-297 yana hana bayyanar cututtuka daban-daban na ƙwayoyin cuta masu kumburi.Ingancin RVX-297 a cikin ƙirar ƙira na ƙayyadaddun ƙayyadaddun kumburi da autoimmunity.
Kusa