4-Chloro-2-fluoro-3-methoxyphenylboronic acid CAS: 944129-07-1
Lambar Catalog | Saukewa: XD93459 |
Sunan samfur | 4-Chloro-2-fluoro-3-methoxyphenylboronic acid |
CAS | 944129-07-1 |
Tsarin kwayoyin halittala | Saukewa: C7H7BClFO3 |
Nauyin Kwayoyin Halitta | 204.39 |
Bayanin Ajiya | yanayi |
Ƙayyadaddun samfur
Bayyanar | Farin foda |
Asay | 99% min |
4-Chloro-2-fluoro-3-methoxyphenylboronic acid wani sinadaran fili ne wanda ke da aikace-aikace daban-daban a cikin hadadden kwayoyin halitta, sunadarai na magani, da kimiyyar kayan aiki.One daga cikin amfanin farko na 4-Chloro-2-fluoro-3-methoxyphenylboronic acid shine a miƙa mulki karfe-catalyzed giciye hada guda biyu halayen.Yana aiki azaman tubalin ginin boronic acid, yana ba da izinin samuwar carbon-carbon ko carbon-heteroatom bond.Misali, ana iya amfani da wannan fili a cikin halayen haɗin kai na Suzuki-Miyaura, inda yake amsawa tare da aryl ko vinyl halides ƙarƙashin palladium catalysis don samar da mahaɗan biaryl.Wadannan halayen haɗin gwiwar giciye suna yadu aiki a cikin haɗakar da hadaddun kwayoyin halitta, ciki har da magunguna da kuma agrochemicals, da kuma gina jiki kayan.The musamman hade da chlorine, fluorine, da kuma methoxy kungiyoyin a cikin tsarin na 4-Chloro-2 -fluoro-3-methoxyphenylboronic acid yana ba da damar haɗa nau'ikan abubuwan haɓaka daban-daban tare da abubuwan da aka kera.Zarra na chlorine na iya aiki azaman ƙungiyar jagora a cikin tafiyar matakai na ƙarfe-catalyzed, yana jagorantar amsa zaɓaɓɓu zuwa takamaiman rukunin yanar gizo a cikin kwayar halitta.Sauya fluorine yana ba da ingantaccen lipophilicity, wanda zai iya yin tasiri ga abubuwan da ake amfani da su na harhada magunguna da inganta yanayin halittarsa.Ƙungiyar methoxy, a gefe guda, na iya aiki a matsayin ƙungiya mai karewa ko shiga cikin sauye-sauyen sinadarai daban-daban.A cikin ilmin sunadarai na magani, 4-Chloro-2-fluoro-3-methoxyphenylboronic acid da abubuwan da suka samo asali suna da sha'awa a matsayin masu takarar magunguna.Ƙungiyoyin aiki irin su chlorine da fluorine na iya daidaita hulɗar mahallin tare da maƙasudin nazarin halittu da inganta kayan aikin sa na harhada magunguna.Bugu da ƙari, ƙungiyar methoxy na iya haɓaka kwanciyar hankali na fili kuma yana ba da gudummawa ga lipophilicity da solubility.Wadannan kaddarorin sun sa 4-Chloro-2-fluoro-3-methoxyphenylboronic acid ya zama mahimmin farawa don haɓaka sababbin magungunan warkewa a fannoni kamar oncology, cututtukan cututtuka, da kumburi. -3-methoxyphenylboronic acid zai iya ba da damar samuwar barga esters boronate, waɗanda aka yi amfani da su a cikin ƙirar kayan da ke da kaddarorin na musamman.Waɗannan kayan zasu iya baje kolin gani, lantarki, ko kaddarorin kuzari, ya danganta da tsarin su da tsarin su.Haɗin 4-Chloro-2-fluoro-3-methoxyphenylboronic acid ko abubuwan da suka samo asali a cikin waɗannan kayan na iya ba da takamaiman ayyuka da haɓaka aikin su. saboda nau'ikan sinadarai iri-iri da yuwuwar samar da kwayoyin halitta da kayan aiki.Matsayinsa a cikin halayen haɗin gwiwa na ƙarfe-catalyzed, haɗe tare da keɓaɓɓen kaddarorin ƙungiyoyin aikin sa, ya sa ya zama kayan aiki mai mahimmanci a cikin haɗaɗɗun kwayoyin halitta da sinadarai na magani.Bugu da ƙari, ƙwayar boronic acid yana ba da damar samuwar esters boronate, waɗanda ke ba da gudummawa ga haɓaka kayan haɓakawa tare da abubuwan da aka keɓance.