Kayayyaki

4-Chlorophenylboronic acid wani nau'in halitta ne wanda ke samun aikace-aikace mai fa'ida a fagage daban-daban, gami da haɗaɗɗun kwayoyin halitta, sunadarai na magani, da kimiyyar kayan aiki.Ya ƙunshi zoben phenyl wanda aka maye gurbinsa tare da ƙungiyar chloro (-Cl) da ƙungiyar boronic acid (-B (OH) 2) .Daya daga cikin amfanin farko na 4-Chlorophenylboronic acid shine rawar da yake takawa a matsayin reagent mai mahimmanci a cikin palladium-catalyzed. halayen haɗin kai, irin su Suzuki-Miyaura da halayen Heck.Wadannan halayen sun haɗa da samuwar carbon-carbon bonds, inda 4-Chlorophenylboronic acid ke aiki azaman tushen boron wanda zai iya haɗawa da nau'ikan electrophiles daban-daban, irin su aryl ko vinyl halides.Wannan yana ba da damar haɓaka nau'ikan mahadi daban-daban, gami da magunguna, agrochemicals, da kayan aiki.Bugu da ƙari, 4-Chlorophenylboronic acid za a iya ƙara gyare-gyaren sinadarai don gabatar da ƙarin ƙungiyoyin aiki.Alal misali, yana iya jurewa amine halayen don samar da 4-chloro-phenylboronates, wanda zai iya zama tsaka-tsaki masu amfani don haɗuwa da nau'o'in abubuwan da ke dauke da nitrogen.Wannan nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'i-aiki) yana haɓaka kayan aiki na 4-Chlorophenylboronic acid, yana ba da damar ƙirƙirar ƙwayoyin ƙwayoyin cuta masu rikitarwa tare da kaddarorin da aka kera.Wani muhimmin aikace-aikacen 4-Chlorophenylboronic acid yana cikin magungunan magani.Ya nuna alƙawarin azaman pharmacophore ko tubalin ginin don haɓaka mahaɗan bioactive.Saboda sinadarin boronate, 4-Chlorophenylboronic acid zai iya samar da haɗin kai mai jujjuyawa tare da kwayoyin da ke ɗauke da diol, kamar carbohydrates da nucleotides.An yi amfani da wannan hulɗar don tsara masu hana enzyme, ligands masu karɓa, da sauran magungunan magunguna.Misali, an samar da masu hana proteasome na tushen boronic acid don maganin myeloma da yawa.A fagen ilimin kimiyyar kayan aiki, 4-Chlorophenylboronic acid ya sami aikace-aikace a cikin gyare-gyaren saman ko haɗin kayan aiki.Ta hanyar amfani da ƙungiyar boronic acid, zai iya samar da ƙaƙƙarfan gungun masu jujjuyawa tare da polyols ko mahadi masu ɗauke da hydroxyl.Ana iya amfani da wannan kadarorin don aikin aiki na sama, irin su ƙirƙirar sutura masu ɗaukar hankali ko kuma shirye-shiryen na'urori masu auna firikwensin don gano carbohydrates ko wasu nazarin. , da kuma kayan kimiyya.Reactivity a cikin samuwar carbon-carbon bond, iyawa don gabatarwar rukuni na aiki, da kuma ikon samar da haɗin kai mai jujjuyawa ya sa ya zama kayan aiki mai mahimmanci ga masu bincike a fannonin kimiyya daban-daban.