Kayayyaki

Manufar wannan binciken ita ce kwatanta ingancin valproate da haloperidol wajen rage yawan tashin hankali a cikin marasa lafiya da aka shafa a cikin sashin gaggawa.Mun sanya majiyyata 80 masu fama da tashin hankali don karɓar ko dai sodium valproate na cikin jijiya (20 mg/kg) ko haloperidol na intramuscular (5 mg/1 ml).An auna tashin hankali a tushe da 30 min bayan allurar ta farko ta amfani da Sikelin kimantawa na Agitation-Calmness (ACES), Matsakaicin Matsala mai Kyau da Rage Ciwon Ciki, da Sikelin Halayyar Halayyar.Ga marasa lafiya 80 da aka bi da su tare da sodium valproate, ma'anar ± SD sashi shine 1541.5 ± 286 MG (kewayon 940-2400).Matsakaicin matsakaicin matsakaici ACES daga tushe zuwa 30 min bayan allurar miyagun ƙwayoyi sune 4.73 (SD = 1.93) don ƙungiyar valproate da 5.45 (SD = 2.09) don ƙungiyar haloperidol (P = 0.028).Ba a sami bambance-bambance masu mahimmanci dangane da ma'anar sauye-sauye na 30 min bayan sa baki don ƙarin ma'aunin tashin hankali biyu.Yawancin marasa lafiya a cikin ƙungiyar haloperidol sun sami kwanciyar hankali mai tsanani (36.2%, P <0.001) da kuma bayyanar cututtuka na extrapyramidal (8.7%, P = 0.007) idan aka kwatanta da ƙungiyar valproate (2.5% don tsangwama mai tsanani, babu mai haƙuri ga bayyanar cututtuka na extrapyramidal).Sakamakon binciken ya nuna cewa a cikin tsarin aikin asibiti na likita na gaggawa, valproate na ciki yana da tasiri kamar haloperidol wajen rage tashin hankali, tare da ingantaccen bayanin martaba.