Albendazole Cas: 54965-21-8
| Lambar Catalog | XD91873 |
| Sunan samfur | Albendazole |
| CAS | 54965-21-8 |
| Tsarin kwayoyin halittala | Saukewa: C12H15N3O2S |
| Nauyin Kwayoyin Halitta | 265.33 |
| Bayanin Ajiya | 2-8 ° C |
| Harmonized Tariff Code | 29332990 |
Ƙayyadaddun samfur
| Bayyanar | Farar crystalline foda |
| Asay | 99% min |
| Wurin narkewa | 208-210 ° C |
| yawa | 1.2561 |
| refractive index | 1.6740 (ƙididdiga) |
| narkewa | A zahiri wanda ba a iya narkewa cikin ruwa, mai narkewa cikin yardar rai a cikin anhydrous formic acid, mai narkewa sosai a cikin methylene chloride, a zahiri maras narkewa a cikin ethanol (kashi 96). |
| pka | 10.72± 0.10 (An annabta) |
| Ruwan Solubility | 0.75mg/L(209ºC) |
Albendazole magani ne da ake amfani da shi don magance cututtukan da ƙwayoyin cuta ke haifarwa.Ana iya ba da shi don maganin ciwon ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (microsporidiosis).
Abun da aka samu na benzimidazole, albendazole magani ne mai faffadan bakan antihelmintic.Yana nuna tasirin antihelmintic akan cestodes masu hankali da nematodes ta hanyar toshe tsarin ɗaukar glucose ta hanyar ƙwayoyin cuta, wanda aka bayyana a cikin raguwar ajiyar glycogen da raguwa na gaba a cikin matakin adenosintriphophate.Sakamakon haka, kwayar cutar ta daina motsi kuma ta mutu.Ana amfani dashi akan kamuwa da cutar Acaris lumbricoides, Ancylostoma duodenale, Necator americanus, Enterobius vermicularis, da Trichuris trichiura.Synonyms na wannan magani sune SKF 62979 da sauransu.
Methyl 5-(propylthio) -2-benzimidazolecarbamate (Eskazole, Zentel) babban anthelmintic ne mai faɗi wanda ba a kasuwa a halin yanzu a Arewacin Amurka.Ana samunsa daga masana'anta akan tushen amfani mai tausayi.Albendazole ana amfani dashi a ko'ina cikin duniya don maganin kamuwa da ciwon hanji.Yana da tasiri a matsayin magani guda ɗaya don ascariasis, Sabuwa da Tsohuwar Cututtukan hookworm, da trichuriasis.Magunguna da yawa tare da albendazole caneradicate pinworm, threadworm, capillariasis, clonorchiasis, da cutar hydatid.Tasirin albendazole antitapeworms (cestodes) gabaɗaya ya fi canzawa kuma ba ya da tasiri.
Albendazole yana faruwa a matsayin farin crystalline foda wanda ba a iya narkewa a cikin ruwa.An inganta shan albendazole ta baki ta hanyar abinci mai kitse.Magungunan yana jurewa da sauri da haɓaka metabolism na farko zuwa sulfoxide, wanda shine nau'i mai aiki a cikin plasma.Kawar da rabin-rai na sulfoxide jeri daga 10 zuwa 15 hours.Babban biliaryexcretion da enterohepatic sake yin amfani da albendazolesulfoxide yana faruwa.Albendazole gabaɗaya ana haƙuri da kyau a cikin maganin kashi ɗaya don nematodes na hanji.Highdotos, tsawan tsawan liyafa da ake buƙata don clonorchiasis na clonorchococccal ccerapy na iya haifar da mummuna, haɓaka enzymes, da kuma alopycia.
Albendazole yana da nau'ikan ayyuka masu yawa a kan nematodes na hanji da cestodes, da kuma hanta masu cutar Opisthorchis sinensis, Opisthorchis viverrini, da Clonorchis sinensis.Hakanan an yi amfani da shi cikin nasara akan Giardia lamblia.Albendazole magani ne mai mahimmanci na cututtukan cystic hydatid (echinococcosis), musamman lokacin tare da praziquantel.Har ila yau, yana da tasiri a cikin maganin neurocysticercosis na kwakwalwa da na kashin baya, musamman idan aka ba shi da dexamethasone. Ana ba da shawarar Albendazole don maganin gnathostomiasis.
