BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT Cas: 100929-71-3
Lambar Catalog | Saukewa: XD90431 |
Sunan samfur | BETA-NADPH TETRA (CYCLOHEXYLAMMONIUM) SALAT |
CAS | 100929-71-3 |
Tsarin kwayoyin halitta | C21H30N7O17P3.4[C6H13N] |
Nauyin Kwayoyin Halitta | 1142.11748 |
Bayanin Ajiya | -20 °C |
Ƙayyadaddun samfur
Bayyanar | Farin foda |
Assay | 99% |
NADPH oxidases iyali ne na enzymes waɗanda ke haifar da nau'in oxygen mai amsawa (ROS).NOX1 (NADPH oxidase 1) da NOX2 oxidases sune manyan tushen ROS a cikin bangon jijiyoyin jini a cikin yanayi irin su hauhawar jini, hypercholesterolemia, ciwon sukari da tsufa, don haka suna da mahimmancin gudummawa ga damuwa na oxidative, rashin aiki na endothelial da kumburi na jijiyoyin jini wanda ke faruwa. gyare-gyaren arterial da atherogenesis.A cikin wannan Bita, muna ci gaba da ra'ayi wanda idan aka kwatanta da yin amfani da maganin antioxidants na al'ada, hana NOX1 da NOX2 oxidases shine hanya mafi kyau don magance matsalolin oxidative.Mun bayyana a taƙaice wasu gama gari da masu hana masu hana NADPH oxidase masu tasowa.Bugu da kari, muna ba da haske mai mahimmancin rawar NADPH oxidase regulatory subunit, p47phox, a cikin ayyukan jijiyoyin jini na NOX1 da NOX2 oxidases, kuma muna ba da shawarar yadda ingantaccen fahimtar takamaiman ma'amalar ƙwayoyin cuta na iya ba da damar haɓaka sabbin magunguna masu zaɓin isoform don hanawa. ko magance cututtukan scular cardiova.