Kayayyaki

Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride wani sinadari ne wanda ke samun aikace-aikace a fagen sinadarai na magani da haɓakar ƙwayoyi.Tsarin kwayoyin halittarsa ​​ya ƙunshi zoben pyrrolidine tare da ƙungiyar tert-butyl a matsayin cis, ƙungiyar ethyl, da ƙungiyoyin carboxylate guda biyu.Ana samun wannan fili yawanci a cikin nau'in gishiri na hydrochloride. Daya daga cikin manyan abubuwan da ake amfani da su na cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride yana cikin haɓakawa da haɓakar kwayoyi masu niyya na tsakiya. tsarin jin tsoro (CNS).Kasancewar zoben pyrrolidine, tare da ƙungiyoyin tert-butyl da ethyl, suna ba da wannan fili tare da abubuwan da ke da tasirin neuroactive.Masu bincike na iya amfani da wannan fili azaman farkon abu don haɗa analogs ko abubuwan haɓaka waɗanda zasu iya zaɓin hulɗa tare da takamaiman masu karɓa ko enzymes a cikin CNS.Ta hanyar gyare-gyaren tsari da masu maye gurbin, za su iya inganta kayan aikin magunguna na fili, haɓaka alaƙar mai karɓa, da kuma inganta yanayin warkewa. Bugu da ƙari, cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride na iya zama. wanda aka yi amfani da shi azaman kayan aiki a cikin nazarin halittu don bincika rawar takamaiman masu karɓa ko enzymes a cikin hanyoyin jijiyoyin jini.Ta amfani da wannan fili a matsayin ligand ko bincike, masu bincike zasu iya yin nazarin alaƙar ɗauri, zaɓi, da tsarin aikin waɗannan masu karɓa ko enzymes.Wannan bayanin yana da mahimmanci don fahimtar tushen ƙwayoyin ƙwayoyin cuta na hanyoyin neuropharmacological da kuma haɓaka sabbin hanyoyin kwantar da hankali waɗanda ke yin niyya ga cututtukan neurodegenerative, yanayin tabin hankali, ko cututtukan jijiyoyin jijiya.Har ila yau, fili yana da yuwuwar aikace-aikace a cikin gano magunguna da ƙididdigar bincike mai girma.Ana iya shigar da shi cikin dakunan karatu na mahadi, waɗanda aka bincika akan maƙasudi daban-daban, kamar masu karɓa ko enzymes, don gano yuwuwar mahaɗan gubar ko masu neman magani.Wannan nunin yana ba da damar gano mahaɗan da ke nuna abubuwan da ake so na pharmacological ko tasirin warkewa. Bugu da ƙari kuma, cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride na iya samun amfani a cikin ci gaban prodrugs.Prodrugs ba su da aiki ko ƙananan mahadi waɗanda aka ƙera don a daidaita su cikin sigar aiki sau ɗaya a cikin jiki.Ta hanyar gyaggyara tsarin wannan fili, masu bincike na iya ƙirƙirar sifofin prodrug waɗanda suka fi kwanciyar hankali, sun inganta yanayin rayuwa, ko kuma suna iya haye membranes na halitta cikin sauƙi.Wannan zai iya haɓaka fa'idodin warkewa na fili da haɓaka abubuwan da ke cikin pharmacokinetic.A taƙaice, cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride wani fili ne tare da yuwuwar aikace-aikace a cikin haɓakar magungunan CNS da aka yi niyya. , a matsayin kayan aiki na kayan aiki don nazarin halittu, a cikin gano magunguna, da kuma ci gaban prodrugs.Tsarinsa na musamman na kwayoyin yana ba da dama don gyarawa da haɓakawa don haɓaka kaddarorin magunguna da ayyukan nazarin halittu.Ƙarfafawa da yuwuwar wannan fili sun sa ya zama muhimmiyar kadara a fagen ilimin sinadarai na magani da haɓakar ƙwayoyi.