Kayayyaki

Cardioprotectant: Creatine phosphate wani muhimmin abu ne da ke samar da makamashi a cikin ƙwayar tsoka da kuma metabolism.Ita ce ajiyar makamashin sinadarai na tsoka mai santsi da tsoka mai tsauri, kuma ana amfani da ita don resynthesis ATP.Phosphocreatinedisodium shine nau'in magani.Sodium Creatine Phosphate, sunan sinadarai N-[imino (phosphono) methyl]-N-methylglycine disodium gishiri, wani wakili ne na cardioprotective wanda Kamfanin Italiya na Ouhui Pharmaceutical Factory ya kaddamar a 1992. Tsarin phosphocreatine yana taka muhimmiyar rawa na jiki, kuma ana amfani dashi sosai. don kariyar zuciya ga marasa lafiya masu fama da ischemia na zuciya ko lokacin aikin tiyata na Chemicalbook, da kuma maganin cututtukan zuciya kamar gazawar zuciya, ciwon zuciya da arrhythmia.Zai iya inganta aikin zuciya da sauye-sauyen yanayin zuciya a cikin marasa lafiya tare da ischemic cardiomyopathy.Ba zai iya samar da makamashi kawai ga sel myocardial lokacin da suke fama da ischemia da hypoxia ba, amma kuma yana kare membranes na sel na zuciya daga mamayewar radicals na oxygen da sauran abubuwa masu cutarwa, wanda zai iya shafar aikin zuciya.Kariyar ciwon zuciya bayan aiki a cikin marasa lafiya da rashin iyawa valvular cuta yana da amfani ga farfadowar aikin zuciya na baya bayan tiyata a cikin marasa lafiya da rashin iyawa.Yin amfani da shi don magance lalacewar ciwon zuciya na zuciya bayan asphyxia na jariri na iya inganta haɓakar enzymes na zuciya da kuma electrocardiogram, kuma yana da tasiri mai kyau da aminci.

Halayen Aiki Wannan samfurin shine ajiyar makamashin sinadarai na zuciya da tsokoki na kwarangwal, kuma ana amfani dashi don sake haɗawa da ATP, yana samar da makamashi don aiwatar da ƙanƙancewar actomyosin, kuma yana taka muhimmiyar rawa a cikin kuzarin kuzarin tsokar tsoka.Rashin isassun makamashi shine muhimmin abu a cikin samuwar da kuma ci gaban rauni na sel myocardial.

1. Yana da tasiri mai mahimmanci na kariya akan aikin systolic na ischemic myocardial, wanda zai iya mayar da cikakkiyar kwangila da sauri rage karfin jini na diastolic.

2. Kula da abun ciki na adenosine triphosphate da creatine phosphate a cikin sel, kuma littafin sinadarai yana kiyaye ajiyar kuzarin zuciya.

3. Rage asarar creatine kinase kuma rage lalacewar kwayar halitta.

4. Yana da anti-peroxidation Properties.

5. Inganta microcirculation na zuciya.Saboda kasancewar babban ƙarfin phosphate bond a cikin creatine phosphate molecules, high-makamashi phosphate bonds iya kai tsaye maida ADP zuwa ATP karkashin aikin creatine phosphate, da kuma kai tsaye ba da makamashi ga jiki don yin aiki nan da nan.A matsayin matsakaicin samfurin glycolysis, sodium fructose diphosphate yana buƙatar taka rawar kai tsaye ta hanyar metabolism na anaerobic.

hanyar roba:

1 Yin amfani da dibenzyl phosphate azaman albarkatun ƙasa, amsa tare da oxalyl chloride don samun dibenzyl oxyphosphoryl chloride.

2 Karkashin aikin triethylamine, dibenzyloxyphosphoryl creatine ethyl ester da aka samu ta hanyar amsawa tare da creatine ethyl ester hydrochloride an cyclized zuwa dibenzyloxyphosphoryl creatinine.

3. Bayan palladium carbon catalyzed hydrogenolysis zuwa debenzylate, amsa tare da sodium hydroxide don samun disodium creatinine phosphate,

4 an sanya shi cikin ruwa zuwa 1 a ƙarƙashin aikin sodium hydroxide.

Yana amfani da: Ya dace don kare ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta.

Mummunan halayen, contraindications da tasirin miyagun ƙwayoyi: waɗanda ke da rashin lafiyar abubuwan wannan samfur an haramta;An haramta wa waɗanda ke da ƙarancin ƙarancin koda na yau da kullun yin amfani da manyan allurai (5-10g/d).Yin allurar cikin sauri fiye da 1g na iya haifar da raguwar hawan jini.Gudanar da yawan ƙwayar cuta yana haifar da babban abincin phosphate, wanda zai iya rinjayar ƙwayar calcium metabolism da ɓoyewar hormones wanda ke daidaita homeostasis, yana rinjayar aikin koda da kuma purine metabolism.