Doxycycline hyclate CAS: 24390-14-5 99% Yellow crystalline foda
Lambar Catalog | XD90368 |
Sunan samfur | Doxycycline hyclate |
CAS | 24390-14-5 |
Tsarin kwayoyin halitta | C22H24N2O8·HCl · 0.5C2H6O · 0.5H2O |
Nauyin Kwayoyin Halitta | 512.94 |
Bayanin Ajiya | 2 zuwa 8 ° C |
Harmonized Tariff Code | Farashin 29413000 |
Ƙayyadaddun samfur
Najasa A | <2% |
Rashin tsarkiB | <2% |
Takamaiman juyawa | -105 zuwa -120 |
pH | 2-3 |
Rashin tsarki C | <0.5% |
Rashin tsarkiD | <0.5% |
Asara akan bushewa | 1.4-2.8% |
Assay | 99% |
Ragowa akan Ignition | <0.4% |
Absorbtivity | 300-335 |
Duk wani kazanta guda daya | <0.5% |
Bayyanar | Yellow crystalline foda |
Rashin tsarki F | <0.5% |
Rashin tsarkiE | <0.5% |
Ethyl Alcohol | 4.5-6% |
Shakar datti | <0.07% |
Samuwar Biofilm akan abutment na hakori na iya haifar da mucositis na peri-implant da kuma peri-implantitis na gaba.Wadannan lokuta ana kula da su ta asibiti tare da maganin rigakafi kamar doxycycline (Doxy).Anan mun yi amfani da hanyar electrochemical na katodic polarization don shafa Doxy a saman farfajiyar kayan aikin haƙori.Filayen da aka lulluɓe Doxy ya nuna fashewar fashewa a cikin salin phosphate-buffered a cikin sa'o'i 24 na farko.Duk da haka, adadi mai mahimmanci na Doxy ya kasance a saman aƙalla makonni 2 musamman akan samfurin 5 mA-3 h tare da adadin Doxy mafi girma, yana ba da shawara duka biyu na farko da na dogon lokaci na bacteriostatic m na rufin rufi.An yi nazarin sunadarai na saman ta hanyar x-ray photoelectron spectroscopy da sakandare ion mass spectrometry.An kimanta yanayin saman ƙasa ta hanyar sikanin sikanin filaye na lantarki da ƙirar haske mai shuɗi.Tsawon lokacin polarization daga 1 h zuwa 5 h kuma mafi girma na halin yanzu daga 1 zuwa 15 mA cm(-2) ya haifar da mafi girman adadin Doxy akan surfa ce.An rufe saman da wani Layer na Doxy kasa da nm 100 ba tare da manyan canje-canje a cikin yanayin saman ba.An yi nazarin kadarar kwayoyin cutar ta Doxy mai rufi ta hanyar biofilm da ƙididdigar girma na planktonic ta amfani da Staphylococcus epidermidis.Samfurori masu rufin doxy sun rage duka tarin biofilm da ci gaban planktonic a cikin al'adun broth, kuma sun hana haɓakar ƙwayoyin cuta akan faranti na agar.Sakamakon antibacterial ya fi karfi don samfurori na 5 mA-3 h da aka rufe tare da adadin Doxy mafi girma idan aka kwatanta da na 1 mA-1 h.Saboda haka, wani saman abutment da aka lulluɓe da Doxy yana da yuwuwar hana kamuwa da ƙwayar cuta lokacin da aka fallasa shi zuwa rami na baki.Doxy-coating na iya zama hanya mai dacewa don sarrafa mucositis na peri-implant da kuma hana ci gaba zuwa peri-implantitis.