Kayayyaki

A cikin binciken yanzu, mun bincika hulɗa ta 'yan wasan kwaikwayo na antrimicraye tare da Membranes na ƙwayoyin cuta na kwastomomi da-ta amfani da dabarar mulmalon ta amfani da dabarar jikinmu.An ƙididdige zaɓin zaɓi da takamaiman halaye masu ɗaurewa na magungunan antimicrobial zuwa membranes na lipid, kuma an bincika sigogin motsin motsi ta hanyar amfani da samfurin amsawar jihohi biyu.An lura da sake yin nazari na ɗaurin motsin motsi.Vancomyicn, teicoplanin, erythromycin, da linezolid sun nuna ƙaramin hulɗa tare da membranes na lipid guda huɗu a cikin tsarin SPR.A gefe guda, analogues vancomycin sun nuna hulɗa tare da samfurin lipid membranes a cikin tsarin SPR.Zaɓaɓɓen da takamaiman halaye na ɗaurin vancomycin analogues zuwa membranes na lipid ana tattauna su dangane da bayanai don ayyukan ƙwayoyin cuta na in vitro da bayananmu game da alaƙar ɗaurin D-alanyl-D-ala tara na bangon pentapeptide ta hanyar SPR.Ana iya kimanta tsarin ayyukan ƙwayoyin cuta akan Staphylococcus aureus da vancomycin-resistant enterococci ta amfani da alaƙar ɗaure da aka samu tare da dabarun SPR ɗin mu.Sakamakon ya nuna cewa hanyar SPR za a iya amfani da ita sosai don tsinkaya halaye masu ɗauri, irin su zaɓi da ƙayyadaddun abubuwa, na yawancin magungunan ƙwayoyin cuta zuwa membranes na lipid.