Furazolidone Cas: 67-45-8
Lambar Catalog | XD91885 |
Sunan samfur | Furazolidone |
CAS | 67-45-8 |
Tsarin kwayoyin halittala | Saukewa: C8H7N3O5 |
Nauyin Kwayoyin Halitta | 225.16 |
Bayanin Ajiya | yanayi |
Harmonized Tariff Code | 2934990 |
Ƙayyadaddun samfur
Bayyanar | Yellow foda |
Asay | 99% min |
Wurin narkewa | 254-256°C (dare) |
Wurin tafasa | 366.66°C (m kiyasin) |
yawa | 1.5406 (ƙananan ƙididdiga) |
refractive index | 1.7180 (ƙididdiga) |
Fp | 2 °C |
narkewa | formic acid: mai soluble 50mg/ml |
pka | -1.98± 0.20 (An annabta) |
M | Hasken Hannu |
max | 365nm (DMSO) (lit.) |
Kwanciyar hankali | Barga.Mai ƙonewa.Wanda bai dace ba tare da magunguna masu ƙarfi masu ƙarfi. |
Bakan maganin kashe kwayoyin cuta na furazolidone yayi kama da na furazolidone.A matsayin maganin rigakafi, yana da tasiri a maganin Salmonella, Shigella, Escherichia coli, Proteus, Streptococcus, da Staphylococcus aureus.Kwayoyin cuta ba su da sauƙi don haɓaka juriya na miyagun ƙwayoyi wannan magani.Hakanan ba shi da juriya tare da maganin rigakafi na aji sulfa.Ana amfani da shi musamman don maganin ciwon daji, enteritis, typhoid, paratyphoid da kuma maganin cututtukan da ke cikin farji trichomoniasis.
2. Samfurin shine maganin fungicides wanda ke da bakan ƙwayoyin cuta mai faɗi.A matsayin maganin hana kamuwa da cuta, yana da tasiri don magance nau'ikan kwayoyin cutar Gram-positive da korau ciki har da Escherichia coli, Bacillus anthracis, da Paratyphoid bacilli.Ba wai kawai yana da tasiri a cikin maganin dysentery, enteritis ba, amma kuma ana amfani dashi don magance cututtuka na farji.A cikin 'yan shekarun nan, yana da tasiri mai kyau don maganin zazzabin typhoid.A matsayin ƙari ga magungunan dabbobi da abin sha, yana da tasirin kashe ƙwayoyin cuta na musamman akan Salmonella, Escherichia coli da Salmonella pullorum kuma yana da wasu tasirin hanawa akan protozoa (kwayoyin coccidia, da sauransu) kuma suna da ƙarancin yuwuwar haɓaka juriya na ƙwayoyi.An yi amfani da ƙaramin adadin furazolidone don wasu aikace-aikace (kamar fenti mai narkewa da ruwa da ɓangaren litattafan almara) azaman fungicides.
3. Magani ne na rigakafin kamuwa da cuta da ake amfani da shi don rigakafin kamuwa da cutar hanji.
4. Furazolidone, a matsayin mai fungicides, yana da nau'in ƙwayar cuta mai yawa.Kwayoyin da suka fi kamuwa da cutar sune Escherichia coli, Bacillus anthracis, sandar paratyphoid, Shigella, da Klebsiella pneumoniae.Salmonella typhi kuma yana kula da shi.Ana amfani da shi musamman don magance cututtukan da ke haifar da ciwon ciki, enteritis, da kwalara.Hakanan za'a iya amfani dashi don maganin typhoid, paratyphoid, giardiasis, da trichomoniasis.Ana iya amfani da haɗe tare da magungunan anti-acid don magance kumburin ciki wanda Helicobacter pylori ya haifar.Properties: rawaya foda ko crystalline foda, wari, da farko m sa'an nan ya zama dan kadan m;dan kadan mai narkewa a cikin ruwa da ethanol;dan kadan mai narkewa a cikin chloroform kuma maras narkewa a cikin ether, mai narkewa a cikin dimethylformamide da nitromethane.Mp: 255 zuwa 259 °C.Rushewa yayin rushewa.
Furazolidone ana amfani dashi a cikin cututtuka na gastrointestinal tract da vaginitis.An fi amfani da shi a cikin ƙasashe masu tasowa don magance cututtukan gudawa na nau'in ilimin etiology daban-daban, amma ba magani ba ne idan an gano takamaiman cutar.Yi amfani da matsayin wakili na biyu a giardiasis kuma a matsayin wani ɓangare na tsarin magunguna da yawa a cikin kamuwa da cutar Helicobacter an ba da shawarar.
3-[(5-Nitrofurylidene)amino] -2-oxazolidinone (Furoxone) yana faruwa a matsayin launin rawaya crystalline foda tare da ɗanɗano mai ɗaci.Ba shi yiwuwa a cikin ruwa ko barasa.Furazolidone yana da aikin bactericidal akan ƙananan ƙwayoyin cuta na hanji, ciki har da S. aureus, E. coli, Salmonella, Shigella, Proteus spp., Enterobacter, da Vibrio cholerae. Yana kuma aiki da protozoan Giardia lamblia.An ba da shawarar don maganin baka na ƙwayoyin cuta ko protozoaldiarrhea wanda kwayoyin cuta ke haifar da su.Matsakaicin adadin manya shine 100 MG sau 4 a rana.
Kadan kaɗan ne kawai na kashi da ake gudanarwa ta baki na furazolidoneis.Kimanin kashi 5% na kashi na baki ana iya ganowa a cikin fitsari a cikin nau'in metabolites da yawa. An ba da rahoton wasu matsalolin gastrointestinal tare da amfani da shi.Ya kamata a guji barasa lokacin da ake amfani da furazolidone saboda miyagun ƙwayoyi na iya hana aldehyde dehydrogenase.