Kayayyaki

Haɗin kai tsakanin magungunan rigakafin ciwon sukari, Metformin da calf thymus DNA (CT-DNA) a cikin (50mM Tris-HCl) buffer an yi nazari ta hanyar UV-Visible absorption, fluorescence, CD spectroscopy da ma'aunin danko.A cikin nazarin fluorimetric, enthalpy da entropy na amsawa tsakanin miyagun ƙwayoyi da CT-DNA sun nuna cewa abin da ya faru shine exothermic (ΔH = -35.4522 kJ mol (-1); ΔS = -49.9523 J mol (-1) K (-1). )).Nazarin dauri na gasa ya nuna cewa miyagun ƙwayoyi na iya sakin Hoechst 33258 gaba ɗaya.Rukunin ya nuna hyperchromism mai sha a cikin bakan UV-Vis tare da DNA.Ƙididdigar ɗaurin ɗaurin ƙididdiga, K (b), wanda aka samo daga nazarin shayarwar UV-Vis shine 8.3 × 10 (4) M (-1).Bugu da ƙari, sauye-sauye a cikin faifan CD a gaban miyagun ƙwayoyi suna nuna kwanciyar hankali na nau'in B na dama na CT-DNA.A ƙarshe, ma'aunin danko ya bayyana cewa ɗaurin hadaddun tare da CT-DNA na iya zama daurin ƙasa, musamman saboda ɗaurin tsagi.Haƙƙin mallaka © 2012 Elsevier BV Duk haƙƙin mallaka.