L-Ornithine L-Aspartate Cas: 3230-94-2
Lambar Catalog | Saukewa: XD91158 |
Sunan samfur | L-Ornithine L-Aspartate |
CAS | 3230-94-2 |
Tsarin kwayoyin halitta | Saukewa: C9H19N3O6 |
Nauyin Kwayoyin Halitta | 265.26 |
Bayanin Ajiya | 2 zuwa 8 ° C |
Harmonized Tariff Code | 29224985 |
Ƙayyadaddun samfur
Bayyanar | Farar crystalline foda |
Asay | >99% |
Takamaiman juyawa | +27 +/-1 |
Karfe masu nauyi | <0.001% |
pH | 6-7 |
Asara akan bushewa | <7% |
Ragowa akan Ignition | <0.2% |
Yanayin Magani | Share |
Ornithine aspartate shine farkon da aka yi amfani da shi a asibiti wajen maganin ciwon hanji da hanta.Tare da tarin ƙwarewar aikace-aikacen asibiti, ornithine aspartate an fi amfani dashi sosai a cikin maganin cututtukan hanta, kuma ya sami daidaitattun tasirin warkewa akan cututtukan hanta, lalacewar hanta da aka haifar da miyagun ƙwayoyi, hanta mai kitse, ciwon hanta na yau da kullun da sauran cututtuka, an yadu sosai. gane da likitoci.
Ornithine aspartate yana samar da wani abu don urea da glutamine kira a cikin vivo.Glutamine shine samfurin detoxification na ammonia, da kuma nau'in ajiya da jigilar ammonia.A karkashin yanayin physiological da pathological, kira na urea da kira na glutamine suna shafar ornithine, aspartic acid da sauran mahadi dicarboxyl.Ornithine yana shiga cikin kusan dukkanin tsarin kunna tsarin urea da detoxification na ammonia.Ana samar da Arginine yayin wannan tsari, sannan a raba urea don samar da ornithine.Aspartic acid yana shiga cikin haɗin nucleic acid a cikin hepatocytes don sauƙaƙe gyaran hanta da suka lalace.Bugu da kari, saboda kai tsaye gabatarwar aspartic acid a kan tsarin rayuwa na tricarboxylic acid sake zagayowar a cikin hanta Kwayoyin, yana inganta makamashi kira a cikin hanta Kwayoyin, wanda shi ne m ga gyara lalace hanta Kwayoyin da accelerates da dawo da hanta aiki.Ci gaba na baya-bayan nan ya nuna cewa aspartate kuma na iya hana ayyukan ƙumburi ta hanyar masu karɓar N-methyl-D-aspartate (NMDA), ta haka ne ya rage tsarin magunguna na hanta mai kumburi.Masu karɓar NMDA wani nau'i ne na masu karɓa na ionotropic excitatory glutamate masu karɓa, wanda ke taka muhimmiyar rawa a cikin tsarin ilimin lissafi kamar watsawar synaptic, synaptic plasticity, koyo da ƙwaƙwalwar ajiya a cikin tsarin kulawa na tsakiya.Binciken ilimin cututtuka na gaba ya kuma tabbatar da cewa aspartate yana inganta haɓakar kumburi a cikin hanta.
Aikace-aikacen asibiti
A fagen ciwon hanta: Ornithine aspartate ana amfani da shi sosai a matsayin maganin hana kumburi da hepatoprotective maganin cututtukan hanta daban-daban, irin su hanta encephalopathy, lalacewar hanta ta hanyar magani, hanta mai kitse, ciwon hanta na yau da kullun, da sauransu. ammonia na jini a cikin marasa lafiya masu fama da ciwon hauka da kuma sauƙaƙan alamun cututtukan neuropsychiatric sannu a hankali suna zama babban magungunan warkewa don maganin cututtukan hanta daban-daban.
Ornithine aspartate shine muhimmin ma'auni don haɗin urea da glutamine.Ornithine iya kunna key enzymes a cikin aiwatar da urea kira - ornithine carbamoyltransferase da carbamoyl phosphate synthase, da kuma inganta ammonia Metabolism cimma detoxification na jini ammonia, aspartic acid a matsayin substrate iya samar da glutamic acid da oxaloacetic acid, glutamine ne detoxification samfurin. ammonia, kuma ita ce ma ajiya da safarar ammonia.Oxaloacetate yana shiga cikin sake zagayowar tricarboxylic acid, yana haɓaka samar da makamashi a cikin ƙwayoyin hanta, kuma yana ba da damar ƙwayoyin hanta da suka lalace don gyarawa, haɓakawa, da dawo da aikin hanta.Ornithine aspartate zai iya inganta aikin hanta yadda ya kamata, rage ammonia na jini, da kuma rage ammonia tare da lactulose da ofloxacin, ta haka yana inganta ƙimar maganin cututtukan hanta, wanda ya cancanci aikace-aikacen asibiti.
Oncology: Tare da ci gaba da canje-canje a cikin nau'o'in da allurai na magungunan chemotherapy, rikice-rikice masu alaƙa da magungunan chemotherapy suma suna fitowa, kuma lalacewar hanta yana ɗaya daga cikin lalacewar gabobin da aka fi sani.Da zarar lalacewar hanta ta faru, zai shafi lafiyar jiki da tunani na marasa lafiya zuwa nau'i daban-daban, hana aiwatar da tsarin ilimin chemotherapy, kuma ya raunana tasirin maganin chemotherapy.A lokuta masu tsanani, gazawar hanta na iya zama barazana ga rayuwa.Ornithine aspartate zai iya inganta lalacewar hanta da ke haifar da magungunan chemotherapy da kuma inganta tasirin maganin ciwon daji.
Filin aikin tiyata: Yin tiyata cuta ce ga dukkan gabobin jikin majiyyaci, kuma lalacewar aikin hanta da aka yi bayan tiyatar ita ma matsala ce ta kowa.Ornithine aspartate zai iya hanawa da kuma magance lalacewar hanta da kuma inganta farfadowa na marasa lafiya bayan tiyata.