Haske kore SF Cas: 5141-20-8 Ruwa mai zurfi mai zurfi
| Lambar Catalog | XD90538 |
| Sunan samfur | Haske kore SF |
| CAS | 5141-20-8 |
| Tsarin kwayoyin halitta | C₃₇H₃₄N₂Na₂O₉S₃ |
| Nauyin Kwayoyin Halitta | 792.86 |
| Bayanin Ajiya | -15 zuwa -20 ° C |
| Harmonized Tariff Code | Farashin 32129000 |
Ƙayyadaddun samfur
| Bayyanar | Zurfin purple foda |
| Assay | 99% |
| Solubility | Mai narkewa a cikin ruwa don ba da bayani mai haske kore |
Don kimanta tsarin da aka tsara da kuma kare lafiyar sababbin dyes don tiyata na intraocular. An haɗa dyes shida a cikin binciken: SF (LGSF) mai haske mai launin rawaya, E68, bromophenol blue (BPB), Chicago blue (CB), rhodamine 6G, rhodulinblau - asali 3 (RDB-B3).An narkar da duk dyes kuma an diluted a cikin daidaitaccen maganin salin saline.Abubuwan da ke ɗaukar haske na kowane rini an auna su a matakin 0.05% tsakanin 200 da 1000 nm.An bincika halayen tabo ta hanyar zubar da ruwan tabarau capsule nama da kuma epiretinal membranes (ERMs), an cire su ta hanyar aiki, tare da yawan rini na 1.0%, 0.5%, 0.2%, da 0.05%.Idanun alade (lokacin mutuwa, sa'o'i 9) suma sun lalace.An ƙididdige yawan guba da ke da alaƙa da launi ta hanyar gwajin launi (MTT) wanda ke auna hana yaduwar kwayar halitta ta epithelium (RPE) (ARPE-19 da ƙananan RPE na mutum na farko, sassan 3-6).Hakanan an ƙididdige iyawar tantanin halitta bisa la'akari da yuwuwar tantanin halitta mai launi biyu.An bincika dyes a cikin ƙididdiga na 0.2% da 0.02% .Duk rini da aka bincika a cikin wannan binciken sun lalata capsules na ruwan tabarau na mutum, an cire su ta cikin ciki;ERMs, bawon a lokacin macular pucker tiyata;da kuma idanun porcine da aka rufe, dangane da maida hankali da aka yi amfani da su.Matsakaicin tsayin tsayin rani na rini yana tsakanin kewayon 527 zuwa 655 nm a adadin 0.05%.Rhodamine G6 da RDB-B3 sun nuna mummunar tasiri a kan yaduwar kwayar halitta ta ARPE-19 a wani nau'i na 0.2% kuma an cire su daga ƙarin bincike a cikin ƙwayoyin RPE na farko.Sauran rinayen rini guda huɗu ba su nuna wani tasiri mai guba akan ARPE-19 da kuma haɓakar ƙwayoyin RPE na farko a adadin 0.2% da 0.02%.Ƙwararren ƙwayar salula ya shafi LGSF yellowish (0.2%) da CB (0.2% da 0.02%).Rini guda biyu (E68 da BPB) sun nuna rashin dacewar da ta dace a cikin vitro. Ƙididdigar tsari na rini don amfani da intraocular yana da alama wajibi ne.A cikin wannan binciken an gano rini guda huɗu tare da halaye masu tasiri masu tasiri, tare da biyu daga cikin waɗannan rinayen da ba su da wani tasiri mai guba akan ƙwayoyin RPE a cikin vitro.
