Kayayyaki

Linagliptin Intermediate F, wanda kuma aka sani da 3-aminopperidine-1-carboxylic acid, wani muhimmin sinadari ne mai mahimmanci a cikin haɗin linagliptin, magani da ake amfani dashi don magance nau'in ciwon sukari na 2.Linagliptin yana cikin nau'in magunguna da aka sani da masu hana dipeptidyl peptidase-4 (DPP-4), waɗanda ke taimakawa daidaita matakan sukari na jini.Yana aiki azaman babban tubalin ginin don ƙirƙirar keɓaɓɓen tsarin sinadarai na linagliptin ta hanyar juzu'i da yawa.Ana amfani da wannan tsaka-tsaki na musamman a cikin haɗin zoben piperidine na tsarin kwayoyin halitta na linagliptin. Da zarar an haɗa shi, linagliptin yana aiki ta hanyar hana ayyukan enzymatic na DPP-4.Masu hana DPP-4 suna aiki ta hanyar hana rushewar hormones na incretin, irin su glucagon-kamar peptide-1 (GLP-1), waɗanda ke da alhakin haɓaka sakin insulin da kuma hana fitar da glucagon.Ta hanyar hana DPP-4, linagliptin yana tsawaita aikin waɗannan hormones na incretin, wanda ke haifar da ingantaccen sarrafa sukarin jini a cikin mutanen da ke da nau'in ciwon sukari na 2. Linagliptin yawanci ana wajabta shi azaman ƙari ga abinci da motsa jiki a cikin sarrafa nau'in ciwon sukari na 2.An san shi don tsawon rabin rayuwar sa, wanda ke ba da damar sauƙi sau ɗaya a kowace rana.An nuna Linagliptin don rage tasirin haemoglobin A1c yadda ya kamata, alamar sarrafa glucose na dogon lokaci, kuma gabaɗaya marasa lafiya suna jurewa sosai. wanda zai iya tasiri sosai ga rayuwar mutanen da ke da nau'in ciwon sukari na 2.Ta hanyar ba da gudummawa ga ƙirƙirar sinadarai na musamman na linagliptin, wannan tsaka-tsakin yana ba da damar samfurin ƙarshe don hana DPP-4 yadda ya kamata da haɓaka sarrafa glycemic. ana amfani dashi don maganin ciwon sukari na 2.Matsayin da yake takawa wajen ƙirƙirar tsarin kwayoyin halitta na linagliptin yana jaddada mahimmancinsa wajen samar da magani wanda zai iya inganta sarrafa sukarin jini da haɓaka sarrafa ciwon sukari.Ta hanyar hana DPP-4, linagliptin yana taimakawa daidaita matakan glucose na jini kuma yana ba da gudummawa ga rayuwar gabaɗayan mutanen da ke da nau'in ciwon sukari na 2.