Metronidazole Cas: 443-48-1
| Lambar Catalog | XD91888 |
| Sunan samfur | Metronidazole |
| CAS | 443-48-1 |
| Tsarin kwayoyin halittala | Saukewa: C6H9N3O3 |
| Nauyin Kwayoyin Halitta | 171.15 |
| Bayanin Ajiya | 2-8 ° C |
| Harmonized Tariff Code | 29332990 |
Ƙayyadaddun samfur
| Bayyanar | Farar crystalline foda |
| Asay | 99% min |
| Wurin narkewa | 159-161 ° C (lit.) |
| Wurin tafasa | 301.12°C |
| yawa | 1.3994 |
| refractive index | 1.5800 (kimanta) |
| Fp | 9 ℃ |
| narkewa | acetic acid: 0.1 M, bayyananne, rawaya mara nauyi |
| pka | pKa 2.62 (H2O, t = 25 ± 0.2, Ba a bayyana ba) |
| Ruwan Solubility | <0.1 g/100 ml a 20ºC |
Metronidazole magani ne na zabi na amebiases, trichomonasis na farji da trichlomonadic urethritis a cikin maza, lambliosis, amebic dysentery, da cututtukan anaerobic da ƙwayoyin cuta ke haifar da su masu kula da miyagun ƙwayoyi.Synonyms na wannan magani sune flagyl, protostat, trichopol, da vagimid.
Metronidazole yana samuwa a matsayin na baka, intravaginal, Topical, da kuma shirye-shiryen parenteral.Kamfanoni da yawa ne ke ƙera shi, amma ana samunsa ta hanyar takardar sayan magani.Bayyanar muhalli ba da gangan ba ne, kuma idan ya faru, da wuya ya haifar da guba.
An yi amfani dashi azaman maganin rigakafi a cikin maganin rosacea.Antiprotozoal (trichomonas).Mai yuwuwar cutar kansar ɗan adam.
Metronidazole, wakili ne na rigakafi da antiprotozoal.Ana amfani da shi ne don magance ko hana cututtuka na tsarin jiki ko na gida wanda kwayoyin anaerobic ke haifar da su, irin su cututtukan cututtuka na anaerobic a cikin rami na ciki, tsarin narkewa, tsarin haihuwa na mace, ƙananan ƙwayar numfashi, fata da laushi mai laushi, kashi da haɗin gwiwa, da dai sauransu. , cututtuka na meningeal, da colitis da ke haifar da amfani da ƙwayoyin cuta suma suna da tasiri.Ana yawan yin maganin tetanus da tetanus antitoxin (TAT).Hakanan ana iya amfani dashi don kamuwa da cutar anaerobic na baka.A ranar 27 ga Oktoba, 2017, an fara jera jerin ƙwayoyin cutar daji da Hukumar Lafiya ta Duniya ta International Agency for Research on Cancer ta buga don tunani, kuma an haɗa metronidazole a cikin jerin nau'ikan carcinogens na aji 2B.A cikin Janairu 2020, an zaɓi metronidazole cikin rukuni na biyu na jerin siyan magunguna na ƙasa.
Metronidazole ita ce wakili mafi inganci da ake samu don maganin mutane masu kowane nau'i na amebiasis, tare da watakila ban da mutumin da yake asymptomatic amma yana ci gaba da fitar da cysts.Wannan yanayin yana buƙatar intraluminal amebicide mai inganci, kamar diloxanide furoate, paromomycin sulfate, ko diiodohydroxyquin.Metronidazole yana aiki akan ƙwayoyin hanji da na waje da kuma trophozoites.
Kodayake an yi amfani da quinacrine hydrochloride don maganin giardiasis, yawancin likitoci sun fi son metronidazole.Furazolidone shine madadin zaɓi.
Metronidazole magani ne na zabi a Turai don cututtukan cututtukan anaerobic;damuwa game da yiwuwar ciwon daji ya haifar da wasu taka tsantsan a cikin amfani da shi a Amurka. Kwanan nan an gano cewa yana da tasiri wajen magance cututtuka na D. medinensis (Guinea worm) da Helicobacter pylori.
Ana kuma amfani da ita a cikin kuraje rosacea, balantidiasis da kamuwa da tsutsotsi na Guinea.T. cututtuka na farji masu jure yanayin da aka saba na buƙatar magani na musamman.
