labarai

Neocuproine reagent shine reagent don ƙaddarar jan ƙarfe, farin ko rawaya-launin ruwan kasa, mai ban haushi.Yafi amfani da matsayin reagent don ƙaddara na cuprous, photometric ƙuduri na jan karfe, ƙayyadaddun matsananci-micro jini sugar;Organic synthesis.An yi amfani da Neocuproine hydrochloride monohydrate wajen auna narkar tagulla a cikin alluran Cu–Ni ta amfani da hanyar launi.Hakanan an yi amfani da shi wajen shirya maganin wakili mai rikitarwa a cikin nazarin ƙididdigar ƙarfin ƙarfin antioxidant a cikin samfuran halitta dangane da rage cunkushewar Cu.Ana iya amfani da shi azaman precursor don shirye-shiryen neocuproine, wanda aka yi amfani dashi azaman reagent na nazari don tantance jan ƙarfe a samfuran muhalli ta amfani da fasaha na spectrophotometric.

Amma duk da haka irin wannan maganin yana da amfani daban-daban a cikin magani. Kwanan nan, Hukumar Kula da Kayayyakin Kiwon Lafiya ta Kasa (NMPA) ta kasa ta amince da Eribulin don tallata don kula da masu fama da ciwon daji na nono da ke faruwa a gida ko kuma masu ciwon daji waɗanda suka sami akalla biyu chemotherapy. tsarin (ciki har da anthracyclines da taxans) a baya.Ya kawo sabon tsarin jiyya a fannin ilimin cutar kansar nono a kasar Sin, yana kuma kawo karin hanyoyin jiyya ga marasa lafiya.
Eribulin shine mai hana tubulin mara taxane.Ba kamar haraji da vinblastine tubulin inhibitors, Eribulin yana da tsarin aiki na musamman, wanda ya sa Eribulin Har yanzu yana da tasiri a cikin marasa lafiya bayan juriya na miyagun ƙwayoyi zuwa yew;Eribulin kuma yana da abubuwan da ba na cytotoxic ba, ciki har da gyaran gyare-gyare na jijiyoyi, ƙara yawan zubar da wasu kwayoyi a cikin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta da dai sauransu.

Daga jimlar halichondrin B, yin amfani da sabbin reagents na jan ƙarfe a matsayin tsaka-tsaki, zuwa gyare-gyaren tsarin Eribulin, zuwa samar da masana'antu na Eribulin, masana kimiyya daga masana kimiyya da kamfanonin harhada magunguna sun shafe fiye da shekaru 20 na bincike.Kayayyakin halitta da aka samu daga teku sun zama magungunan da za su iya magance cutar kansa.Bincike da haɓakar Eribulin saboda sabon reagent na jan ƙarfe yana da mahimmanci a matsayin babban matsakaicin API ɗin sa.Sabuwar jan ƙarfe na jan ƙarfe yana da babbar rawa a matsayin matsakaicin magunguna da reagent don tsaftace manyan kayan kida.

Tsarin kwayoyin halitta na Eribulin ya ƙunshi cibiyoyi 19 na chiral, kuma matakan haɗin gwiwar sun kai tsayin matakai 62.Ya zuwa yanzu, Eribulin har yanzu masana'antu suna kallonsa a matsayin mafi hadaddun magungunan marasa peptide da aka samar da tsantsar sinadarai, kuma ana iya kiransa Dutsen Everest a cikin masana'antar hada sinadarai.
Nasarar jeri na Eribulin yana nuna sabon tsayin da kamfanonin harhada magunguna za su iya cimma a cikin haɗin sinadarai da samar da masana'antu.Har ila yau yana kawo ƙarin bincike da ra'ayoyin jiyya da zaɓuɓɓuka ga likitocin Sinawa.Ana fatan cewa a cikin aikin asibiti na gaba, sabon maganin chemotherapeutic Eribulin zai iya kawo sabon bege ga masu cutar kansar nono.