Penicillin G potassium gishiri CAS: 113-98-4 99% Farin foda
| Lambar Catalog | Saukewa: XD90351 |
| Sunan samfur | Penicillin G potassium gishiri |
| CAS | 113-98-4 |
| Tsarin kwayoyin halitta | Saukewa: C16H17KN2O4S |
| Nauyin Kwayoyin Halitta | 372.48 |
| Bayanin Ajiya | yanayi |
| Harmonized Tariff Code | Farashin 29411000 |
Ƙayyadaddun samfur
| Asara akan bushewa | <1.0% |
| Launi na Magani | Ba mai tsananin launi ba fiye da ƙarfin Y2 ko YG2 na kewayon tunani |
| pH | 5-7.5 |
| Abubuwa masu alaƙa | <1.0% |
| Assay | 99% |
| Ƙarfi | 1440-1680u/mg |
| Bayyanar | Fari zuwa kusan fari crystalline foda |
| Bayyanar Magani | Bai wuce opalescent fiye da dakatarwar tunani 1 |
| watsawa | NLT 90% |
| Butyl acetate | NMT 0.05% |
| Butanol | NMT 0.12% |
e wanda aka bayyana a baya cewa kwayar cutar autoinducer, wanda aka gano a matsayin 1,3-diaminopropane (1,3-DAP), Penicillium chrysogenum da Acremonium chrysogenum ne suka ɓoye.Yin amfani da al'adun fermentor masu sarrafa pH mun lura a cikin wannan aikin cewa 1,3-DAP da spermidine a fili suna haɓaka biosynthesis na benzylpenicillin a cikin P. chrysogenum, duka a cikin ƙayyadaddun kuma a cikin hadaddun hanyoyin samar da penicillin.Dukansu 1,3-DAP da spermidine, amma ba putrescine (1,4-diaminobutane), suna haifar da haɓaka mai ƙarfi a cikin matakan kwafin penicillin biosynthetic genes pcbAB, pcbC da penDE.Wadannan polyamines ba su shafar bayyanar pH-stress regulator pacC gene, don haka ban da cewa tasirin 1,3-DAP da spermidine saboda gyare-gyaren tsarin kula da pH.Bayyanar kwayoyin halittar penicillin biosynthetic guda uku yana raguwa sosai a cikin mutan mai-ƙara-ƙasa na P. chrysogenum, wanda ke samar da ƙananan matakan benzylpenicillin.Abin sha'awa, 1,3-DAP da spermidine sun sake komawa tasirin maye gurbi na laeA, suna maido da matakan samar da penicillin gaba ɗaya.Bugu da ƙari kuma, 1,3-DAP da spermidine sun inganta maganganun laeA a cikin ƙwayar iyaye kuma sun mayar da matakan laeA a cikin laeA ƙwanƙwasa mutant.Haɗa waɗannan sakamakon sun nuna cewa tasirin haɓakar ƙwayoyin inducer 1,3-DAP da spermidine ana yin su, aƙalla a wani ɓangare, ta hanyar haɓakar furci na laeA, mai kula da duniya wanda ke aiki ta hanyar epigenetically akan bayyanar ƙwayoyin metabolite na biyu. ta hanyar sake tsara tsarin heterochromatin.
