Rapamycin daga Streptomyces hygroscopicus CAS: 53123-88-9 Fari zuwa kashe-fari ko rawaya crystalline foda
| Lambar Catalog | Saukewa: XD90356 |
| Sunan samfur | Rapamycin daga Streptomyces hygroscopicus |
| CAS | 53123-88-9 |
| Tsarin kwayoyin halitta | Saukewa: C51H79NO13 |
| Nauyin Kwayoyin Halitta | 914.17 |
| Bayanin Ajiya | -20 °C |
| Harmonized Tariff Code | Farashin 294200000 |
Ƙayyadaddun samfur
| Assay | 99% |
| Bayyanar | Fari zuwa fari-fari ko rawaya crystalline foda |
Rapamycin, wani magani wanda aka nuna yana kara yawan rayuwa a cikin mice, yana hana manufar rapamycin (TOR) hanya, babbar hanyar da ke daidaita girman kwayar halitta da matsayi na makamashi.An yi hasashe cewa rapamycin da ƙuntatawa na abinci (DR) suna tsawaita rayuwa ta hanyoyi / hanyoyi iri ɗaya.Yin amfani da bincike na microarray, mun kwatanta rubutun farin adipose nama daga berayen da aka ciyar da rapamycin ko DR-diet na tsawon watanni 6.Multidimensional scaling da kuma nazarin taswirar zafi sun nuna cewa rapamycin ba shi da wani tasiri a kan rubutun idan aka kwatanta da DR.Misali, kwafi shida ne kawai rapamycin ya canza sosai yayin da berayen da ke ciyar da DR sun nuna gagarumin canji a sama da 1000 kwafin.Yin amfani da bincike na hanyar hazaka, mun gano cewa DR biosynthesis stearate da siginar rhythm circadian sun canza sosai.Bincikenmu yana nuna cewa DR, amma ba rapamycin ba, yana da tasiri a kan rubutun nama na adipose, yana nuna cewa waɗannan magudi guda biyu suna ƙara tsawon rayuwa ta hanyoyi / hanyoyi daban-daban.
