Sitagliptin CAS: 486460-32-6
Lambar Catalog | Saukewa: XD93423 |
Sunan samfur | Sitagliptin |
CAS | 486460-32-6 |
Tsarin kwayoyin halittala | Saukewa: C16H15F6N5O |
Nauyin Kwayoyin Halitta | 407.31 |
Bayanin Ajiya | yanayi |
Ƙayyadaddun samfur
Bayyanar | Farin foda |
Asay | 99% min |
Sitagliptin magani ne wanda ke cikin rukunin magungunan da ake kira dipeptidyl peptidase-4 (DPP-4) inhibitors.Ana amfani da shi da farko a cikin sarrafa nau'in ciwon sukari na 2.Ciwon sukari yana faruwa ne lokacin da jiki ya kasa daidaita matakan sukari na jini yadda ya kamata, wanda ke haifar da yawan glucose a cikin jini.Wadannan hormones suna ƙara haɓakar insulin kuma suna rage samar da glucagon, a ƙarshe yana haifar da ƙarin sarrafa matakan sukari na jini.Ta hanyar hana enzyme DPP-4, sitagliptin yana ba da damar incretin hormones su ci gaba da aiki na tsawon lokaci, don haka inganta sarrafa sukarin jini. Hanyar farko ta sitagliptin ita ce ta baka, kuma ana iya sha tare da ko ba tare da abinci ba.Matsakaicin da ƙwararrun ma'aikatan kiwon lafiya suka tsara zai dogara ne akan abubuwan haƙuri na mutum ɗaya, kamar tsananin ciwon sukari da sauran magunguna da ake amfani da su.Yana da mahimmanci a bi umarnin da aka tsara a hankali kuma kada a daidaita adadin ba tare da tuntuɓar mai ba da lafiya ba. Yawancin lokaci ana amfani da Sitagliptin azaman ƙari ga abinci da motsa jiki a cikin sarrafa nau'in ciwon sukari na 2.An fi yin amfani da shi tare da gyare-gyaren salon rayuwa da sauran magungunan antidiabetic, irin su metformin.Ta hanyar haɗa hanyoyin aiki daban-daban, kamar sitagliptin's DPP-4 hanawa da haɓaka metformin na ji na insulin, ana iya samun ingantaccen sarrafa glycemic. An nuna tasirin sitagliptin a cikin sarrafa matakan sukari na jini a cikin gwaje-gwajen asibiti da yawa.Nazarin ya nuna cewa yana iya rage matakan glucose na azumi da bayan cin abinci (bayan cin abinci), rage matakan haemoglobin glycated (HbA1c), da kuma inganta sarrafa glycemic gabaɗaya. kamar ciwon kai, cututtuka na numfashi na sama, da damuwa na gastrointestinal kamar tashin zuciya ko gudawa.Kamar kowane magani, munanan halayen rashin lafiyar da ba kasafai ba amma illa mai tsanani na iya faruwa, don haka yana da mahimmanci a ba da rahoton duk wani sabon yanayi ko mai tsanani ga ƙwararrun kiwon lafiya da sauri. .A matsayin mai hana DPP-4, yana taimakawa inganta sarrafa glycemic ta hanyar tsawaita ayyukan incretin hormones.Lokacin amfani dashi tare da gyare-gyaren salon rayuwa da sauran magungunan rigakafin ciwon sukari, sitagliptin na iya zama ingantaccen kayan aiki don sarrafa matakan sukari na jini da sarrafa nau'in ciwon sukari na 2.Kulawa na kusa da tuntuɓar mai ba da lafiya suna da mahimmanci don sakamako mafi kyau.