Kayayyaki

Don bincika cututtukan ƙwayoyin cuta na keɓancewar Neisseria gonorrhoeae daga Saskatchewan, Kanada, ta amfani da Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), da kuma tantance ƙungiyoyi tsakanin cututtukan cututtukan ƙwayoyin cuta (AMS) da takamaiman nau'ikan nau'ikan iri (STs). , wanda aka tattara tsakanin 2003 da 2008, an buga ta NG-MAST.An haɗa STs idan ɗaya daga cikin allurarsu ya zama gama gari kuma ɗayan ya bambanta da ≤1% a cikin jerin DNA.An ƙaddara AMS ta hanyar dilution agar (CLSI) zuwa maganin rigakafi guda bakwai. N gonorrheae warewar an warware su zuwa 82 mutum NG-MAST STs da 18 NG-MAST ST kungiyoyin tare da kungiyoyi 25, 3655, 921, 3654, 3657 da 3656 kunshi 513. /320) na wariya.N keɓancewar gonorrheae mai saurin kamuwa da duk magungunan rigakafin da aka gwada suna da mahimmanci (p<0.05) waɗanda ke da alaƙa da ST 25 (87%).Sauran ƙungiyoyi masu mahimmanci tsakanin ST da AMS sun haɗa da: ST 3654 da keɓancewa tare da ƙananan ƙarancin hanawa na ≥0.03 mg / L zuwa ceph alosporins na ƙarni na uku;ST 3711 (100%) da TRNG;da ST/group 3654 (43%) da juriya na chromosomal ga penicillin da tetracycline.Yawancin NG-MAST STs/rukuni suna da alaƙa da mahimmanci tare da keɓancewa tare da juriya na chromosomal ga tetracycline.Warewa masu jure wa ciprofloxacin (n=5) da azithromycin (n=2) sun bayyana azaman STs guda ɗaya.An lura da ƙungiyoyi masu mahimmanci a tsakanin mutum STs, jima'i da shekarun mai haƙuri, da kuma yanki na yanki da na wucin gadi. An gano ƙungiyoyi tsakanin N gonorrheae AMS da NG-MAST STs kuma yana iya zama da amfani wajen tsinkayar AMS a yanki.Saboda STs a ƙasashe daban-daban sun bambanta sosai, amfani da NG-MAST don tsinkayar AMS a duniya yana buƙatar ƙarin nazari.