Streptozocin CAS: 18883-66-4 Kodiddigar rawaya crystalline foda
Lambar Catalog | Saukewa: XD90359 |
Sunan samfur | streptozocin |
CAS | 18883-66-4 |
Tsarin kwayoyin halitta | Saukewa: C8H15N3O7 |
Nauyin Kwayoyin Halitta | 265.22 |
Bayanin Ajiya | -20 °C |
Harmonized Tariff Code | 29419090 |
Ƙayyadaddun samfur
Assay | 99% |
Bayyanar | Kodadde rawaya crystalline foda |
Ciwon sukari mellitus yana da alaƙa da ƙananan kumburi na yau da kullun da damuwa na oxidative.Bupleurum Polysaccharides (BPs), keɓe daga Bupleurum smithii var.parvifolium yana da anti-mai kumburi da anti-oxidative Properties.Duk da haka, an san kadan game da tasirin warkewa akan ciwon sukari.A cikin wannan gwaji, an bincika tasirin BP akan rage ciwon sukari da kuma hanyoyin da ke da tushe.An kafa samfurin berayen masu ciwon sukari ta hanyar allurar intraperitoneal na streptozotocin (nauyin 100 mg/kg) na kwana biyu.An zaɓi beraye masu matakan glucose na jini sama da 16.8mmol/L don gwaje-gwaje.An yi amfani da berayen masu ciwon sukari da baki tare da BPs (30 da 60 mg/kg) sau ɗaya a rana don kwanaki 35.BPs ba kawai rage matakan glucose na jini sosai ba, har ma sun karu na insulin insulin da hanta glycogen a cikin berayen masu ciwon sukari idan aka kwatanta da samfurin mice.Bugu da ƙari, gudanar da BPs ya inganta maganganun insulin kuma yana danne apoptosis a cikin ƙwayar ƙwayar ƙwayar cuta na ciwon sukari.Binciken ilimin tarihi ya kara nuna cewa BPs sun kare pancreatic da hanta daga lalacewa mai kumburi da kumburi.Wadannan sakamakon sun ba da shawarar cewa BPs suna kare ƙwayoyin β na pancreatic da hanta hanta da kuma inganta ciwon sukari, wanda ke da alaƙa da kayan aikin anti-oxidative da anti-inflammatory.