Tazobactam Cas: 89786-04-9
Lambar Catalog | Saukewa: XD92373 |
Sunan samfur | Tazobactam |
CAS | 89786-04-9 |
Tsarin kwayoyin halittala | Saukewa: C10H12N4O5S |
Nauyin Kwayoyin Halitta | 300.29 |
Bayanin Ajiya | -15 zuwa -20 ° C |
Harmonized Tariff Code | Farashin 29419000 |
Ƙayyadaddun samfur
Bayyanar | Fari zuwa kashe-fari foda |
Asay | 99% min |
Ruwa | <0.5% |
Takamaiman juyawa | +127 zuwa +139 |
Karfe masu nauyi | <20ppm |
Ragowa akan Ignition | <0.1% |
Jimlar ƙazanta | <1.0% |
Tazobactam shine penicillanic acid sulfone wanda yayi kama da koyarwar sulfactam.Yana da mafi ƙarfi β-lactamaseinhibitor fiye da sulbactam kuma yana da ɗan ƙaramin aiki mai faɗi fiye da clavulanic acid.Yana da rauni mai rauni sosai.Tazobactam yana samuwa a cikin ƙayyadaddun ƙayyadaddun, alluran allura tare da piperacillin, babban nau'in penicillin mai girma wanda ya ƙunshi rabo na 8: 1 na piperacillin sodium zuwa tazobactamsodium ta nauyi kuma ana sayar da shi a ƙarƙashin sunan kasuwanci Zosyn. Magungunan magunguna na magungunan biyu sunyi kama da juna.Dukansu suna da gajeriyar rabin rayuwa (t1/2 ~1 hour), suna da ƙarancin furotin, suna da ɗanɗano kaɗan kuma suna fitar da sifofi marasa aiki a cikin fitsari cikin ƙima mai yawa.
Alamun da aka yarda da haɗin gwiwar piperacillin-tazobactam sun haɗa da maganin appendicitis, postpartumendometritis, da cututtukan kumburi na pelvic wanda ke haifar da beta-lactamase-samar da E. coli da Bacteroides spp., cututtukan tsarin fata da fata wanda β-lactamase-samar S.aureus, da ciwon huhu wanda β-lactamase ke haifar da nau'in cutar mura na H. mura.