Kayayyaki

Tert-butyl 4- (6-(6- (1-butoxyvinyl)) -8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido [2,3-d] pyrimidin-2-yl) amino) pyridin-3-yl) piperazine-1-carboxylate wani fili ne tare da yuwuwar yuwuwar a cikin sinadarai na magani da haɓakar ƙwayoyi.Tsarinsa mai rikitarwa yana nuna nau'ikan aikace-aikace iri-iri.Wannan fili yana ƙunshe da core piperazine-1-carboxylate, wanda aka saba amfani da shi a cikin sinadarai na magani saboda yanayin da ya dace da kuma fa'idar yiwuwar amfani da miyagun ƙwayoyi.Kasancewar nau'in piperazine yana ba da damar yin hulɗa tare da masu karɓa daban-daban da enzymes, yana mai da shi dan takara mai ban sha'awa don bunkasa magungunan warkewa.The 6- (1-butoxyvinyl) -8-cyclopentyl-5-methyl-7-oxo-7, 8-dihydropyrido [2,3-d] pyrimidin-2-yl rukuni a cikin tsarin yana ba da damar yin amfani da magunguna.Irin waɗannan abubuwan pyrido [2,3-d] pyrimidine an yi nazari sosai don abubuwan da suke da su na anti-inflammatory, antiviral, da anticancer.Ƙungiyoyin cyclopentyl da methyl suna ba da gudummawa ga lipophilicity na fili, wanda zai iya haɓaka haɓakar ƙwayar salula da kuma bioavailability. Ƙungiyar tert-butyl ester tana ba da kwanciyar hankali ga fili kuma za'a iya canzawa cikin sauƙi zuwa wasu ƙungiyoyi masu aiki, suna ba da damar ƙarin gyare-gyare ko ƙaddamarwa.Wannan sassaucin ra'ayi yana da mahimmanci a cikin ilmin sunadarai na magani, kamar yadda yake ba da damar haɓakar abubuwan da suka fi dacewa da zaɓaɓɓu. Ƙungiyar pyridin-3-yl a cikin tsarin yana aiki a matsayin mai yuwuwar ligand ga masu karɓa daban-daban, irin su G protein-coupled receptors (GPCRs).Wannan yana nuna cewa fili na iya samun tasiri akan hanyoyin siginar intracellular kuma za'a iya ci gaba da bincike don yiwuwarsa a matsayin mai daidaitawa ko antagonist na takamaiman masu karɓa da ke cikin yanayin cututtuka. Tsarin gaba ɗaya na tert-butyl 4- (6- (6-). (1-butoxyvinyl) -8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido [2,3-d] pyrimidin-2-yl) amino) pyridin-3-yl) piperazine-1-carboxylate karin bayanai yuwuwar sa a cikin ci gaban novel therapeutics.Yana ba da dama don bincikar hanawar enzyme, ɗaurin mai karɓa, da daidaitawa na matakai daban-daban na nazarin halittu.Tare da ƙarin bincike da ingantawa, wannan fili zai iya zama mai yiwuwa a matsayin jagorar jagora don ci gaba da magungunan da ke fama da ciwon daji, kumburi, ko wasu cututtuka.Siffofin tsarin sa na musamman da kuma ayyukan ilimin halitta sun sa ya zama fili mai ban sha'awa don ƙarin bincike da ci gaba a fagen ilimin kimiyyar magani.A ƙarshe, tert-butyl 4- (6- (6- (1-butoxyvinyl)) -8-cyclopentyl- 5-methyl-7-oxo-7,8-dihydropyrido [2,3-d] pyrimidin-2-yl) amino) pyridin-3-yl) piperazine-1-carboxylate yana riƙe da alƙawari a matsayin fili mai mahimmanci don ci gaban ƙwayoyi.Tsarinsa mai rikitarwa da yuwuwar ayyukan ilimin harhada magunguna sun sa ya zama ɗan takara mai ban sha'awa don ƙarin bincike a matsayin wakili na warkewa don cututtuka da yanayi daban-daban.