Tetracycline hydrochloride CAS: 64-75-5 99% Yellow crystalline foda
| Lambar Catalog | Saukewa: XD90366 |
| Sunan samfur | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Tsarin kwayoyin halitta | C22H24N2O8 · HCl |
| Nauyin Kwayoyin Halitta | 480.90 |
| Bayanin Ajiya | -15 zuwa -20 ° C |
| Harmonized Tariff Code | Farashin 29413000 |
Ƙayyadaddun samfur
| Kammalawa | Ya dace da BP2013, EP7, USP38 |
| Karfe masu nauyi | <0.005% |
| Tsaftace Guda Daya | <0.1% |
| Ganewa | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Asara akan bushewa | <2.0% |
| Ragowar sauran ƙarfi | n-Butanol <3000ppm |
| Assay | BP2013/EP7 99% |
| Sulfate ash | <0.5% |
| Takamaiman jujjuyawar gani | -240 zuwa -255° |
| Ƙarfi | USP 38:> 900ug/mg |
| Jimlar ƙazanta | <5% |
| Bayyanar | Yellow crystalline foda |
| 4-epianhydrotetracycline | <2% |
| Iyakar ƙananan ƙwayoyin cuta | Ya bi |
| 4-Epiteracycline | <3% |
| Anhydrotetracyline | <0.5% |
| Chlortetracycline hydrochloride | <0.5% |
| Residual Solvent | <100ppm |
An ƙaddamar da haɓakar juriya na ƙwayoyin cuta zuwa wuce haddi da rashin amfani da magungunan ƙwayoyin cuta.Staphylococci wani bangare ne na flora na yau da kullun amma kuma masu yuwuwar ƙwayoyin cuta ne waɗanda suka zama da gaske juriya ga sanannun maganin rigakafi.An ba da shawarar juriya a cikin coagulase korau staphylococci (ConS) don haɓakawa saboda matsi mai kyau na zaɓi biyo bayan maganin ƙwayoyin cuta.Wannan binciken ya binciki kasancewar magunguna tara da aka fi amfani da su a cikin fitsarin ɗan adam daga marasa lafiya a asibitoci biyu a Ghana dangane da juriya na CoNS.An yi samfurin fitsari da CoNS (n = 246 da n = 96 bi da bi) daga marasa lafiya a asibitoci biyu a Ghana.An gano CoNS ta amfani da tabo na Gram, gwajin coagulase, da MALDI-TOF/MS, kuma an ƙaddara rashin lafiyar ƙwayoyin cuta zuwa ƙwayoyin cuta na 12 da aka saba amfani da su ta hanyar rarraba diski.Haka kuma an ɓullo da hanyar nazari don tantance magungunan kashe ƙwayoyin cuta guda tara da aka fi amfani da su a Ghana ta hanyar amfani da tsantsa-ph ase haɗe tare da HPLC-MS/MS ta amfani da ionization na feshin lantarki.An lura da mafi girman mitar juriya ga CoNS don penicillin V (98%), trimethoprim (67%), da tetracycline (63%).S. haemolyticus shine keɓe mafi yawan jama'a (75%), sai S. epidermidis (13%) da S. hominis (6%).S. haemolyticus kuma shine nau'in da ke nuna mafi girman juriya (82%).69% na keɓancewar CoNS sun kasance masu jure magunguna da yawa (≧ 4 maganin rigakafi) kuma 45% na CoNS sun kasance masu juriya na methicillin.An gano magungunan ƙwayoyin cuta a cikin kashi 64% na samfuran fitsarin da aka bincika (n = 121) inda aka fi gano maganin rigakafi da aka fi sani da ciprofloxacin (30%), trimethoprim (27%), da metronidazole (17%).Babban binciken da aka yi na wannan binciken shi ne cewa yawancin maganin rigakafi da aka gano a cikin fitsari ya fi yawa fiye da yadda marasa lafiya suka yi amfani da su kuma yawancin S. haemolyticus mai juriya ya kasance fiye da sauran nau'in CoNS masu juriya lokacin da aka gano magungunan antimicrobial a cikin fitsari.
