Thiamphenicol Cas: 15318-45-3
Lambar Catalog | Saukewa: XD92378 |
Sunan samfur | Thiamphenicol |
CAS | 15318-45-3 |
Tsarin kwayoyin halittala | Saukewa: C12H15Cl2NO5S |
Nauyin Kwayoyin Halitta | 356.22 |
Bayanin Ajiya | yanayi |
Harmonized Tariff Code | Farashin 29414000 |
Ƙayyadaddun samfur
Bayyanar | Farar crystalline foda |
Asay | 99% min |
Matsayin narkewa | 163 ° C - 167 ° C |
Karfe masu nauyi | ≤10pm |
Asara akan bushewa | ≤1.0% |
Takamaiman jujjuyawar gani | -21°-24° |
Chloride | ≤0.02% |
Thiamphenicol shine chloramphenicol na ƙwayoyin cuta mai faɗi, wanda ya fi tasiri ga ƙwayoyin gram-korau fiye da ƙwayoyin gram-positive.A dakin da zafin jiki, shi ne fari zuwa kashe-fari crystalline foda ko crystal, wanda za a iya sauri da kuma gaba daya sha ta baka adminstration, kazalika da shi ne excreted yafi a cikin samfurin daga fitsari domin metabolism.Ana amfani da shi a asibiti don maganin cututtukan numfashi, urinary fili, hanta da gallbladder, typhoid da sauran tiyata na hanji, likitan mata da cututtukan ENT.Musamman a cikin ƙananan cututtuka ya fi tasiri.Yana da tsarin sinadarai iri ɗaya tare da chloramphenicol.methyl sulfone ya maye gurbin nitro na chloramphenicol, wanda ya rage yawan guba, kuma a cikin vivo aikin sa na kashe kwayoyin cuta ya fi chloramphenicol ƙarfi sau 2.5-5.Ga kwayoyin cutar gram-tabbatacce, irin su streptococcus pneumoniae da hemolytic streptococcus, yana da tasirin kashe kwayoyin cuta mai karfi sosai, yayin da kwayoyin cutar gram-korau, irin su Neisseria gonorrhoeae, meningococcus, huhu Bacteroides, E. coli, Vibrio cholerae, Shigella da cutar mura. Hakanan yana da tasiri mai ƙarfi na ƙwayoyin cuta.Ga kwayoyin cutar anaerobic, Rickettsia da amoeba, yana da tasirin kashe kwayoyin cuta a wani lokaci.Yana da tsarin rigakafin ƙwayoyin cuta iri ɗaya tare da chloramphenicol, wanda galibi yana hana haɓakar furotin na kwayan cuta.Ana shan wannan magani da sauri ta hanyar sarrafa baki, wanda ya kai ga mafi girma a cikin jini a cikin sa'o'i biyu.Rabin rayuwarsa shine awa 5, wanda ya fi chloramphenicol tsayi.Kwayoyin suna da cikakkiyar juriya gare shi da kuma chloramphenicol, yayin da kwayoyin cutar suna da wasu abubuwan juriya da su da kuma tetracycline.
Thiamphenicol kuma yana da tasiri mai ƙarfi na rigakafi, wanda shine kyakkyawan maganin rigakafi.Tsarin aikinsa ya bambanta sosai tare da sauran wakilai na rigakafi.Sakamakon immunosuppressive ya ninka sau da yawa fiye da chloramphenicol.Yana iya zama azaman mai haɓaka mai inganci don amsawar dasawa da dashen allogeneic ta tiyata.