Kayayyaki

Binciken phytochemical na dukan shuka na Lepisorus contortus (Kristi) Ching ya haifar da keɓance sababbin phenylethanoid glycosides guda biyar (1-5), kowannensu yana ɗauke da rukunin caffeoyl, sabon flavonoid glycoside (10), da 14 sanannun mahadi (6-9). da 11-15, syringic acid, vanillic acid, phloretic acid, diplopterol, da β-sitosterol).Wannan shine rahoton farko na phenylethanoid glycosides daga dangin Polypodiaceae.An kimanta mahaɗin 1-15 don yuwuwar cutar kansa ta chemopreventive dangane da ikon su na hana ƙwayar cuta necrosis factor alpha (TNF-α) -induced NF-κB ayyukan, samar da nitric oxide (NO), da aromatase, quinone reductase 2 (QR-2). ), da ayyukan COX-1/-2.Quercetin-3-O-β-d-glucoside (15) ya nuna hanawa akan QR2 tare da ƙimar IC (50) na 3.84 μM, wanda ya tabbatar da kaempferol / quercetin glycosides a matsayin mahadi masu aiki don hana QR2.Har ila yau, fili ya nuna aikin NF-κB tare da ƙimar IC (50) na 33.6 μM.Bugu da ƙari, mahadi 1, 2, 4, da 6 sun nuna aikin ar omatase tare da ƙimar IC (50) na 30.7, 32.3, 26.8, da 35.3 μM, bi da bi.