4-Amino-1-((2R,4S,5R) -4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl) pyrimidin-2 (1H) -daya Cas: 951-77-9
| Lambar Catalog: | XD90580 |
| Cas: | 951-77-9 |
| Tsarin kwayoyin halitta: | Saukewa: C9H13N3O4 |
| Nauyin Kwayoyin Halitta: | 227.22 |
| samuwa: | A Stock |
| Farashin: | |
| Shiri: | 1g USD10 |
| Kunshin girma: | Neman Magana |
Ƙayyadaddun samfur
| Bayyanar | Farar crystalline foda |
| Assay | 99% |
| Matsayin narkewa | 196 ° C - 200 ° C |
Thymidine phosphorylase (TP, EC 2.4.2.4) ya gane tsarin ma'auni tare da ƙayyadaddun ƙayyadaddun bayanai, ta hanyar duka tushe da ribosyl moieties.Sauya 3'-OH na thymidine ya yi tasiri sosai akan ayyukan sa na motsa jiki tare da TP.Juyawar pyrimidine nucleosides tare da gyare-gyaren ginshiƙan tushe zuwa nau'in 1-phosphate mai dacewa ba shi da kyau.Ayyukan ƙungiyar masu barin sun ragu tare da haɓaka ƙamshi na tushen tushen pyrimidine, saboda ƙaƙƙarfan wahala wajen daidaita tushe ta amino acid na gida zuwa wurin aiki.Sauyawa ƙungiyoyin ayyuka na 3' da 5' sun yi ƙoƙarin rage yawan amsawa da jujjuya kaso tare da TP.Musamman rukunin ribosyl 3' hydroxyl yana da mahimmancin tsari don ɗaure ma'aunin ta hanyar enzyme.Ƙididdigar motsin motsi ta nuna a sarari K(m) da ƙananan ƙimar V (max) akan maye gurbin ƙungiyar hydroxyl 3' tare da hydrogen.
