Kayayyaki

Biofilms sun ƙunshi sel na ƙwayoyin cuta waɗanda ke ɓoye a cikin haɗin kai, matrix polymeric na extracellular.Poly-beta (1,6) -N-acetyl-d-glucosamine (PNAG) shine babban ɓangaren matrix biofilm a cikin nau'ikan ƙwayoyin cuta.A cikin wannan binciken mun binciki kaddarorin jiki da sinadarai na PNAG matrix a cikin biofilms da aka samar a cikin vitro ta hanyar gram-negative porcine na numfashi pathogen Actinobacillus pleuropneumoniae da gram-tabbatacce na'urar pathogen Staphylococcus epidermidis.An ƙayyade tasirin PNAG akan kwararar ruwa mai yawa ta hanyar auna ƙimar juzu'in ruwa ta hanyar biofilms waɗanda aka haɓaka a cikin na'urorin tacewa na centrifugal.Yawan convection na ruwa ya kasance mafi girma a cikin biofilms da aka haɓaka a gaban PNAG mai lalata enzyme tarwatsawa fiye da na biofilms da aka tsara ba tare da enzyme ba, yana nuna cewa PNAG yana rage yawan ruwa mai yawa.PNAG kuma ya toshe jigilar mahallin ammonium quaternary cetylpyridinium chloride (CPC) ta cikin fim ɗin.Haɗewar CPC zuwa fina-finai na biofilms yana ƙara hana haɗuwar ruwa tare da toshe jigilar azo rini Allura ja.Bioactive CPC an samo shi da kyau daga biofilms ta hanyar jiyya tare da 1 M sodium chloride.A hade, waɗannan binciken sun nuna cewa CPC tana amsawa kai tsaye tare da matrix PNAG kuma ta canza halayenta na zahiri da na sinadarai.Sakamakonmu yana nuna cewa PNAG yana taka muhimmiyar rawa wajen sarrafa yanayin yanayin halittu na biofilms kuma yana iya ba da gudummawa ga ƙarin hanyoyin da suka shafi biofilm kamar juriya na biocide.