Clopidogrel camphorsulfonate CAS: 28783-41-7
Lambar Catalog | Saukewa: XD93353 |
Sunan samfur | Clopidogrel camphorsulfonate |
CAS | 28783-41-7 |
Tsarin kwayoyin halittala | Saukewa: C26H32ClNO6S2 |
Nauyin Kwayoyin Halitta | 554.11 |
Bayanin Ajiya | yanayi |
Ƙayyadaddun samfur
Bayyanar | Farin foda |
Asay | 99% min |
Clopidogrel camphorsulfonate wani fili ne na magunguna tare da dabarar sinadarai C16H16ClNO2S · C10H16O4S.An fi sani da Clopidogrel S-oxide camphorsulfonate ko Clopidogrel CAMS.Wannan fili shine tushen chiral na clopidogrel, wanda shine maganin antiplatelet da ake amfani dashi da yawa. Amfani da farko na Clopidogrel camphorsulfonate shine a matsayin wani abu mai aiki a cikin samar da magungunan antiplatelet.Yana aiki ta hanyar hana haɗuwar platelet, hana samuwar jini, da rage haɗarin abubuwan da ke faruwa na zuciya da jijiyoyin jini.Filin yana nufin mai karɓar P2Y12 na musamman akan platelet, don haka yana toshe tsarin kunnawa da hana haɗuwar platelet.Wannan tsarin aiki yana sa Clopidogrel camphorsulfonate yayi tasiri wajen hana thrombosis na arterial da rage abubuwan da ke faruwa na cututtukan zuciya da jijiyoyin jini, gami da bugun zuciya da bugun jini.Da zarar an ci shi, yana jure wa canjin rayuwa a cikin hanta, wanda ke haifar da samuwar metabolite mai aiki.Wannan metabolite mai aiki sannan ba zai sake dawowa ba ga mai karɓar P2Y12, yana yin tasirin antiplatelet na tsawon lokaci.Ginin yana da tsawon lokaci mai tsawo na aiki, yana buƙatar dosing sau ɗaya a kowace rana a mafi yawan lokuta. A cikin aikin asibiti, Clopidogrel camphorsulfonate an fi wajabta wa marasa lafiya tare da ciwo mai tsanani na jijiyoyin jini, irin su angina marar tsayayye da ciwon zuciya na zuciya, ko kuma wadanda suka yi fama da ciwon zuciya na percutaneous. shiga tsakani (PCI) tare da sanya stent.Hakanan ana amfani dashi sosai don hana faruwar abubuwan thrombotic a cikin marasa lafiya waɗanda ke da tarihin bugun jini ko cututtukan jijiya na gefe.Yin amfani da Clopidogrel camphorsulfonate sau da yawa ana haɗa shi tare da ƙarancin aspirin don haɓaka maganin antiplatelet.Yana da mahimmanci a lura cewa Clopidogrel camphorsulfonate ya kamata a yi amfani da shi kawai a ƙarƙashin kulawar ƙwararrun ma'aikatan kiwon lafiya, saboda yana iya hulɗa tare da wasu magunguna ko samun contraindications a wasu takamaiman. yawan masu haƙuri.Matsakaicin sashi da tsawon lokacin jiyya na iya bambanta dangane da yanayin likita na mutum, kuma kulawa na yau da kullun na aikin platelet da gwajin jini na iya zama dole don tabbatar da ingantaccen tasirin warkewa. musamman wadanda ke da alaƙa da thrombosis arterial.Kaddarorin sa na antiplatelet da zaɓin hanawa na mai karɓar P2Y12 sun sa ya zama magani mai inganci don rage haɗarin cututtukan cututtukan zuciya mara kyau.Koyaya, kamar kowane fili na magunguna, yakamata a yi taka-tsan-tsan wajen amfani da shi, kuma majiyyata yakamata su bi shawarwarin masu ba da lafiya da jagora.