Folic Acid Cas: 59-30-3 99%
| Lambar Catalog | Saukewa: XD90435 |
| Sunan samfur | Folic acid |
| CAS | 59-30-3 |
| Tsarin kwayoyin halitta | Saukewa: C19H19N7O6 |
| Nauyin Kwayoyin Halitta | 441.40 |
| Bayanin Ajiya | yanayi |
| Harmonized Tariff Code | 29362900 |
Ƙayyadaddun samfur
| Bayyanar | Yellow ko orange crystalline foda |
| Assay | 99% |
| Ruwa | 5.0 - 8.5% |
| Chromatographic tsarki | <2.0% |
| Solubility | A zahiri maras narkewa a cikin ruwa da yawancin kaushi na halitta.Ya narke a cikin acidic dilute kuma a cikin maganin alkaline |
| Ragowa akan Ignition | <0.3% |
A cikin wannan binciken, thermosensitive da folate functionalized poly (ethylene oxide) -b-poly (propylene oxide) -b-poly (ethylene oxide) -ploy (N-isopropylacrylamide-co-hydroxyethyl methacrylate) (FA-Pluronic-PNH) copolymer ya kasance. hada.An tabbatar da tsari da nauyin kwayoyin halitta na copolymer ta 1H NMR, FT-IR da GPC, bi da bi.Ƙananan zafin jiki mai mahimmanci (LCST) na copolymer ya kasance 39.8 digiri C. Ta hanyar amfani da doxorubicin (DOX) a matsayin samfurin samfurin, folate mai karɓa mai karɓa na DOX wanda aka ɗora a kan copolymer.Miceles mara kyau da DOX da aka ɗora su duka sun nuna kusan sifofi kuma matsakaicin diamita ya kasance 35 nm da 50 nm, bi da bi.Halayen sakin in vitro na micelles da aka ɗora a cikin DOX sun dogara da zafin jiki kuma adadin sakin DOX a digiri 42 C (sama da LCST) ya fi wannan a 37 digiri C (a ƙasa LCST).Bugu da ƙari kuma, ƙididdigar cytotoxicity na DOX da DOX da aka ɗora wa micelles kyauta akan layin ƙwayoyin cutar kansa na mahaifa na mahaifa HeLa da layin kwayar cutar kansar huhu na ɗan adam A549 ya nuna cewa folate yana haɓaka ɗaukar wayar salula na micelles a cikin sel da aka yi niyya waɗanda ke bayyana masu karɓar folate masu yawa.
