Kayayyaki

Don bayyana tsarin farko na ma'adinan dentin, an bincika tasirin hanawa na 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) akan ma'adinan dentin.An yi wa berayen (100 g) allurar subcutaneously tare da HEBP (8 mg P/kg) don 7 ko 14 d, kuma an sarrafa incisors don Ca histochemistry da/ko microscopy na lantarki.Incisors da aka yi wa HEBP sun nuna tsani-kamar madadin layuka na ma'adinai da ma'adinan ma'adinai a ƙarshen apical.GBHA ta bayyana matsakaicin halayen Ca a cikin matrix ɗin circumpulpal da ba ma'adinai ba inda microscopy na lantarki ya bayyana arziƙi na ɗimbin rabe-raben raƙuman raƙuma-kamar lantarki mai yawa.Mantle dentin matrix mara ma'adinai ba shi da kyau ga Ca amma ya ƙunshi nau'ikan matrix vesicles (MVs) masu cike da ma'adinan ma'adinai da/ko amorphous.Ma'adinan ma'adinai na circumpulpal dentin ya faru ba tare da ɗimbin ɗigon mantle na MV ba a cikin samfuran da abin ya shafa.Bayananmu suna ba da shaidar histochemical na yuwuwar mallakar Ca-dauri na matrix dentin matrix da kuma rashin sa a cikin maƙarƙashiyar rigar inda MV-tsakanin ma'adinai ke faruwa.A cikin mantle dentin, HEBP baya tsoma baki tare da haɓakar crystal a cikin MVs amma yana hana fitowar sa bayan fashewar membrane.An ba da shawarar cewa matrix na matrix na circumpulpal yana da yuwuwar yin ma'adinai daban-daban na ma'adinan ma'adinan MV na mantle dentin, kodayake MVs sun ƙayyade wurin farko da lokacin ma'adinan dentin.