Iodonitrotetrazolium chloride CAS: 146-68-9
| Lambar Catalog | XD90473 |
| Sunan samfur | Iodonitrotetrazolium chloride |
| CAS | 146-68-9 |
| Tsarin kwayoyin halitta | Saukewa: C19H13ClIN5O2 |
| Nauyin Kwayoyin Halitta | 505.70 |
| Bayanin Ajiya | 2 zuwa 8 ° C |
| Harmonized Tariff Code | Farashin 32129000 |
Ƙayyadaddun samfur
| Ganewa | H-NMR |
| Bayyanar | Hasken rawaya zuwa foda orange |
| Assay | >99% |
| Solubility | Share bayani |
Interferon-induced transmembrane protein 1 (IFITM1) yana ɗaya daga cikin membobin dangin furotin da ke haifar da interferon.A cikin wannan binciken, mun ba da rahoton cewa haɓakar IFITM1 magana a cikin ciwon daji na launi na ɗan adam (CRC) yana da alaƙa da alaƙa da kumburin lymph na CRC da metastasis mai nisa da kuma matakin ci gaba na asibiti.Mahimmanci, haɓakar magana ta IFITM1 wani abu ne mai zaman kansa don rashin rayuwa.Don bincika hanyoyin ƙwayoyin ƙwayoyin cuta, mun nuna cewa yawan bayyanar IFITM1 a cikin ƙwayoyin CRC an inganta su, yayin da aka hana bugun IFITM1 magana, ƙaurawar cell / mamayewa da ƙari a cikin vitro.Bugu da ƙari kuma, mun gano Caveolin-1 (CAV1) a matsayin maƙasudin ƙasa na IFITM1-induced cell mamayewa, kamar yadda knockdown na CAV1 shafe siIFITM1 matsakanci hana mamaye cell a cikin CRC Kwayoyin.Bugu da ƙari, a cikin ƙungiyar CRC na marasa lafiya na 229, ma'anar IFITM1 ta bambanta da ma'anar CAV1.Waɗannan sakamakon sun ba da shawarar cewa IFITM1 yana haɓaka haɓakar haɓakar ƙwayoyin CRC, kuma alama ce mai yuwuwar hasashen da maƙasudin warkewa ga CRC.
