L-Histidine Cas: 71-00-1 98.5% Farin lu'ulu'u ko lu'ulu'u na foda
Lambar Catalog | XD90301 |
Sunan samfur | L-Histidine |
CAS | 71-00-1 |
Tsarin kwayoyin halitta | Saukewa: C6H9N3O2 |
Nauyin Kwayoyin Halitta | 155.15 |
Bayanin Ajiya | yanayi |
Harmonized Tariff Code | 29332990 |
Ƙayyadaddun samfur
Assay | 98.5% min |
Bayyanar | Farin lu'ulu'u ko lu'ulu'u masu launin fari |
Daraja | USP39 |
Takamaiman juyawa | +12.6 ° zuwa +14.0 ° |
Ganewa | Infrared sha |
pH | 7.0 - 8.5 |
SO4 | <= 0.03% |
Fe | <= 30ppm |
Asara akan bushewa | <=0.2% |
Ragowa akan Ignition | <=0.1% |
Cl | <= 0.05% |
Karfe masu nauyi (PB) | <= 15pm |
Abubuwan da ke da alaƙa | Ba a sami fiye da 0.5% na kowane ƙazanta ba;Ba fiye da 2.0% na jimlar ƙazanta ana samun su ba |
shi quadruplex kafa jerin G-arziƙi ana rarraba su ba daidai ba a cikin kwayoyin halittar ɗan adam.Wadatar su a cikin masu tallata oncogenic da telomeres sun haifar da sha'awar yin niyya ga G-quadruplex (GQ) don maganin ciwon daji.Anan, mun gabatar da ƙididdiga na ƙididdigewa kan haɓakawa da haɓakar tsarin GQ waɗanda aka auna ta hanyar kyalli ɗaya.Bugu da ƙari, muna danganta waɗannan kaddarorin zuwa ga ligands masu niyya na GQ da G4 resolvase 1 (G4R1) haɗin furotin.Sakamakonmu ya nuna cewa duka madauki (wanda ba G abubuwan da aka gyara ba) tsayi da jerin suna ba da gudummawa ga daidaitawar GQ.Alamun kwayoyin halitta guda na ainihin lokacin suna bayyana cewa yanayin nadawa shima ya dogara ne akan abun da ke cikin madauki.Mun nuna cewa GQ-tsayawa ƙananan ƙwayoyin cuta, N-methyl mesoporphyrin IX (NMM), analog ɗin sa, NMP da furotin G4R1 suna ɗaure zaɓaɓɓu zuwa daidaitaccen tsarin GQ.Abubuwan da muka gano suna nuni zuwa ga sarƙaƙƙiyar nadawa GQ wanda ke tafiyar da tsayin madauki da jeri da kuma yadda tsarin GQ ke ƙayyadad da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙwayoyin cuta da furotin.