Lipase daga porcine pancreas CAS: 9001-62-1 Brown zuwa m foda
Lambar Catalog | Saukewa: XD90387 |
Sunan samfur | Lipase daga porcine pancreas |
CAS | 9001-62-1 |
Tsarin kwayoyin halitta | N/A |
Nauyin Kwayoyin Halitta | N/A |
Bayanin Ajiya | 2 zuwa 8 ° C |
Harmonized Tariff Code | Farashin 35079090 |
Ƙayyadaddun samfur
Ash | <12% |
AS | <2mg/kg |
Pb | <2mg/kg |
Abubuwan Ruwa | <8% |
Assay | 99% |
Ayyukan Enzyme | > 30000u/g |
Bayyanar | Brown zuwa beige foda |
Coliform Group | <30MPH/100g |
Don amfani da bincike kawai, ba don amfanin ɗan adam ba | amfani da bincike kawai, ba don amfanin ɗan adam ba |
Canje-canjen metabolism na triglyceride (TG) a cikin ƙwayoyin tsoka mai santsi (SMC) mai yuwuwa za a daidaita su tare da wasu nau'ikan phenotype, kodayake wannan ba a bayyana shi ba.Adipose triglyceride lipase (ATGL) yana aiwatar da manyan ayyuka na catalytic na TG a cikin ƙwayoyin adipotic da marasa adipotic.A cikin binciken na yanzu, mun ware SMC daga ATGL-rashin mice (ATGL(-/-) mSMC).ATGL (-/-) mSMC ya nuna tarin TG ba tare da bata lokaci ba tare da ƙananan amsawar mitogenic da kuma maganganun tsoka mai laushi (SMA) idan aka kwatanta da ATGL (+/+) mSMC.Kashi na _-galactosidase tabbataccen sel masu haɗe-haɗe kuma an ƙaru a cikin ATGL(-/-) mSMC.PCR na ainihi wanda ya biyo baya ta hanyar nunawa tare da nazarin tsararru na DNA da aka mayar da hankali ya nuna bayanin da aka tsara na glucokinase (1.7-fold), lipoprotein lipase (3.8-fold) da interleukin-6 (3.7-ninki) da kuma ƙayyadaddun ƙayyadaddun yanayin ci gaban endothelial na jijiyoyin jini. factor-A (0.2-ninka), nau'in I collagen (0.5-ninka), da kuma canza yanayin girma-_ (0.4-ninka) a cikin ATGL (-/-) mSMC idan aka kwatanta da ATGL (+/+) mSMC.Bayan haka, an yi ƙoƙarin canja wurin ectopic gene na ɗan adam ATGL ta amfani da doxycycline (Dox) -regulatable myc-DDK-tagged adenovirus vector (AdvATGL).Cutar cututtuka na AdvATGL ya haifar da raguwar tarawar TG tare da haɓakar amsawar mitogenic da maganganun SMA, kuma ya ragu a cikin lambobi masu ganewa a cikin ATGL (-/-) mSMC.Haka kuma, karkataccen tsarin bayyanar da kwayoyin halitta a cikin ATGL(-/-) mSMC ana iya gyara shi.Bayananmu sun ba da shawarar cewa ATGL (-/-) mSMC suna da nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in kifi) yana da nau'in phenotype wanda zai iya kasancewa da alaka da cututtuka na jijiyoyin jini.Plasticity na SMC phenotypes da ke da alaƙa da metabolism na lipid zai iya zama manufa ta warkewa.