Kayayyaki

Rukunin Europium (III) da terbium (III), sune [Eu (dpq) (DMF) 2 (NO3) 3] (1), [Eu (dppz) 2 (NO3) 3] (2), [Tb (dpq) (DMF) 2Cl3] (3), da [Tb (dppz) (DMF) 2Cl3] (4), inda dipyrido [3,2-d: 2',3'-f] quinoxaline (dpq a 1 da 3) , Dipyrido [3,2-a: 2',3'-c] phenazine (dppz a cikin 2 da 4) da N, N'-dimethylformamide (DMF) an keɓe su, suna bayyana daga bayanan ilimin kimiyyar lissafi, nazarin haske da hulɗar su. tare da DNA, sunadarin furotin albumin na jini da kuma aikin cirewar DNA wanda aka haifar da hoto.Tsarin kristal na X-ray na rukunin gidaje 1-4 suna nuna tsayayyen tsarukan Ln(3+) na mononuclear.Eu (3+) a cikin [Eu (dpq) (DMF) 2 (NO3) 3] (1) da [Eu (dppz) 2 (NO3) 3] (2) kamar [Eu (dppz) 2 (NO3) 3 ] · dppz (2a) ya ɗauki tsarin dodecahedron mai daidaitawa guda goma tare da bidentate N, N-donor dpq ligand, DMF biyu da uku NO3 (-) anions a cikin 1 da biyu bidentate N, N-donor dppz ligands da uku NO3 ( -) anions a cikin 2. Complexes 3 da 4 suna nuna tsarin octahedron guda bakwai masu daidaitawa guda bakwai inda Tb (3+) ya ƙunshi bidentate dpq/dppz ligands, DMF biyu da uku Cl (-) anions.Gine-ginen suna da haske sosai a cikin yanayi suna nuna ingantaccen hoto mai cike da kuzarin canja wurin makamashi daga eriyar dpq/dppz zuwa Ln(3+) don samar da jahohi masu ban sha'awa na tsawon rai don halayen f → f.Siffar luminescence da aka warware na lokaci-lokaci na rukunin gidaje 1-4 suna nuna nau'ikan ƙunƙun hayaki waɗanda aka danganta ga (5)D0 → (7)F (J) da (5) D4 → (7) F (J) ff sauye-sauye na Eu (3) +) da Tb (3+) ions bi da bi.An ƙayyade adadin kwayoyin ruwa na ciki-spher (q) daga ma'aunin rayuwa na luminescence a cikin H2O da D2O yana tabbatar da halayen ligand-musanya tare da ruwa a cikin bayani.Rukunin suna nuna mahimmancin ɗaurin ɗaurin kai ga CT-DNA yana ba da ƙimar ɗauri akai-akai a cikin kewayon 1.0 × 10 (4) -6.1 × 10 (4) M (-1) a cikin tsari 2, 4 (dppz)> 1, 3 (dpq).Bayanan dauri na DNA suna ba da shawarar tsagi na DNA yana ɗaure tare da yanayin tsaka-tsaki na ɓangarori.Dukkanin hadaddun kuma suna nuna haɓakar ɗaure (K(BSA) ∼ 10(5) M(-1)) zuwa furotin na jini na bovine (BSA).Ƙarfin igiyoyin haske na lokaci-gated luminescence spectral bands suna haɓaka sosai tare da ƙara yawan tattarawar DNA a cikin matsakaiciyar ruwa mai ruwa saboda ƙaurawar ruwan da aka daure akan hulɗa tare da DNA, don haka rage ƙarancin haske ta hanyar OH oscillator.Complexes 1-4 da kyau yana manne supercoiled (SC) ds-DNA zuwa madauwari mai nick (NC) akan fallasa zuwa hasken UV-A na 365 nm ta hanyar samuwar iskar oxygen guda (1) O2 da hydroxyl radicals (HO˙) kamar yadda nau'in oxygen mai amsawa a ƙananan ƙwayoyin micromolar a ƙarƙashin yanayin ilimin lissafi.