Kayayyaki

S- (+) - Methyl- (2-chlorophenyl) [(2- (2-thienyl) amino] acetate hydrochloride, wanda kuma aka sani da S- (+) -Clopidogrel, wani fili ne na magunguna tare da tsarin sinadarai na C16H16ClNO2SH·HCl Yana da wani nau'i na chiral na clopidogrel, wanda shine mahimmancin maganin antiplatelet. Amfani da farko na S- (+) -Methyl- (2-chlorophenyl) [(2- (2-thienyl)amino] acetate hydrochloride ne a matsayin mai aiki. Sinadari a cikin samar da magungunan zuciya da jijiyoyin jini, musamman magungunan antiplatelet, yana aiwatar da tasirinsa na warkewa ta hanyar hana haɗuwar platelet, hana samuwar ɗigon jini, da rage haɗarin cututtukan zuciya da jijiyoyin jini. Muhimmiyar rawa a cikin kunnawa da tarawar platelet Ta hanyar haɗakar da wannan mai karɓar ba tare da juyowa ba, S- (+) - Methyl- (2-chlorophenyl) [(2- (2-thienyl)amino] acetate hydrochloride yana hana kunna platelet kuma yana hana samuwar platelet. Wannan yanayin aikin ya sa ya zama magani mai mahimmanci don hana al'amuran thrombotic a cikin marasa lafiya da ke cikin haɗari mai yawa, irin su wadanda ke da tarihin ciwo mai tsanani, ciwon ischemic, ko cututtuka na jijiyoyin jini.S-(+) -Methyl- (2-chlorophenyl) [(2- (2-thienyl)amino] acetate hydrochloride yawanci ana gudanar da shi ta baki ta hanyar allunan ko capsules.Bayan an sha, ana samun canjin rayuwa a cikin hanta don samar da metabolite mai aiki.Wannan metabolite mai aiki yana ɗaure ba tare da juyowa ba ga mai karɓar P2Y12, yana aiwatar da tasirin sa na antiplatelet na tsawon lokaci.Ana yin amfani da fili sau ɗaya a kowace rana, ko dai a matsayin magani na musamman ko a hade tare da wasu magungunan antiplatelet, kamar aspirin. Yana da mahimmanci a lura cewa S- (+) -Methyl- (2-chlorophenyl) [(2-2-2) -thienyl) amino] acetate hydrochloride yakamata a yi amfani da shi kawai a ƙarƙashin jagorancin ƙwararrun ƙwararrun kiwon lafiya, saboda amfani da shi na iya samun yuwuwar.