Streptavidin daga Streptomyces avidinii CAS: 9013-20-1
Lambar Catalog | Saukewa: XD90329 |
Sunan samfur | Streptavidin daga Streptomyces avidinii |
CAS | 9013-20-1 |
Tsarin kwayoyin halitta | Saukewa: C14H17BrClNO2S |
Nauyin Kwayoyin Halitta | 378.71 |
Bayanin Ajiya | -15 zuwa -20 ° C |
Harmonized Tariff Code | Farashin 35040090 |
Ƙayyadaddun samfur
Bayyanar | Farin foda |
Assay | 99% |
Don amfani da bincike kawai, ba don amfanin ɗan adam ba | amfani da bincike kawai, ba don amfanin ɗan adam ba |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) wanda ke dauke da rukunin alkyne an nuna shi azaman tushen tushen manufa-takamaiman hanawa na sialidases.Ester-kare analog DFSA (PDFSA) shine madaidaicin membrane-permeable na DFSA wanda aka tsara don amfani dashi a cikin sel masu rai, kuma an nuna shi don samar da haɗin gwiwa tare da ƙwayoyin cuta, ƙwayoyin cuta, da sialidases na ɗan adam.Za'a iya haɗa haɗin fluorosialyl-enzyme tare da biotin azide-annexed ta hanyar danna amsa kuma an gano ta takamaiman siginar rahotanni na streptavidin.Liquid chromatography-mass spectrometry/mass spectrometry bincike akan gutsutsayen peptide tryptic yana nuna cewa 3-fluorosialyl moiety yana gyara ragowar tyrosine na sialidases.An yi amfani da DFSA don nuna kamuwa da kamuwa da mura da kuma ganewar asali na kamuwa da kwayar cutar kwayar cutar zuwa maganin oseltamivir acid na maganin mura, yayin da aka yi amfani da PDFSA a cikin hoto na canje-canjen ayyukan sialidase a cikin sel masu rai.