Tiamulin 98% Cas: 125-65-5
| Lambar Catalog | XD91893 |
| Sunan samfur | Tiamulin 98% |
| CAS | 125-65-5 |
| Tsarin kwayoyin halittala | Saukewa: C22H34O5 |
| Nauyin Kwayoyin Halitta | 378.5 |
| Bayanin Ajiya | -20°C |
| Harmonized Tariff Code | 2918199090 |
Ƙayyadaddun samfur
| Bayyanar | Farin foda |
| Asay | 99% min |
| Wurin narkewa | 170-1710C |
| alfa | D24 +20° (c = 3 a cikin abs ethanol) |
| Wurin tafasa | 482.8 ± 45.0 °C (An annabta) |
| yawa | 1.15± 0.1 g/cm3 (An annabta) |
| narkewa | DMSO:> 10mg/mL (dumi) |
| pka | 12.91± 0.10 (An annabta) |
| aikin gani | [α]/D +30 zuwa +40° (c=1; CH2Cl2) |
Pleuromutilin wani diterpene ne wanda nau'ikan baidomycete da dama suka samar, musamman jinsin Pleurotus, wanda aka gano a 1951. na aiki.Pleuromutilin yana hana haɗin furotin ta hanyar ɗaure zuwa yanki na V na 23S rRNA kuma wannan ya haifar da haɓaka yawancin analogues na sintetik a matsayin sabon maganin rigakafi, kamar tiamulin da retapamulin.
An yi amfani da Pleuromutilins irin su tiamulin da valnemulin na ɗan lokaci a cikin magungunan dabbobi don magance cututtukan alade.Kwanan nan an gabatar da wani nau'in pleuromutilin semisynthetic, retapamulin, a matsayin magani na gaba don cututtukan cututtukan Gram a cikin mutane.Pleuromutilins suna hana ayyukan peptidyl transferase na ƙwayar cuta ta 50S ribosomal subunit ta ɗaure zuwa rukunin A.
