Kayayyaki

Don bincika tasiri mai amfani na haɗuwa da butyrate, Lactobacillus casei, da L-carnitine a cikin samfurin ƙwayar cuta. An raba berayen zuwa ƙungiyoyi bakwai.Ƙungiyoyi huɗu sun karɓi butyrate na baka, L-carnitine, Lactobacillus casei da haɗuwa da wakilai uku na kwanaki 10 a jere.Sauran ƙungiyoyin sun haɗa da sarrafawa mara kyau da inganci da ƙungiyar sham.Macroscopic, histopathological jarrabawa, da kuma biomarkers irin su tumor necrosis factor-alpha (TNF-α) da interlukin-1β (IL-1β), myeloperoxidase (MPO), thiobarbituric acid reactive abubuwa (TBARS), da ferric rage ikon plasma (FRAP). ) an ƙaddara a cikin hanji. Haɗin haɗin gwiwa ya nuna tasiri mai mahimmanci a cikin kawar da colitis idan aka kwatanta da sarrafawa.Gabaɗaya canje-canje a cikin raguwar TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / MG protein, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg/mg furotin, P), <0.0.5. ± 0.03 vs 0.49 ± 0.04 μg/mg sunadaran, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg furotin, P <0.05), da haɓakar FRAP (23.46 ± 5.2 ± 1.2 μl / mo) , P <0.05) yana goyan bayan fifikon haɗin gwiwar haɗin gwiwa a kwatanta da sarrafawa.Ko da yake monotherapies kuma sun kasance masu tasiri wajen inganta alamun colitis, haɗin haɗin gwiwar ya fi kyau a inganta alamun alamun damuwa na colon oxidative ciki har da FRAP, TBARS, da MPO.Haɗin da ke yanzu shine cakuda mai dacewa don kula da colitis na gwaji kuma ya kamata a gwada shi a ciki. saitin asibiti.