A cikin ci gaba da neman lafiyayyen magungunan rigakafin ciwon sukari, algae na ruwa ya zama tushe mai mahimmanci wanda ke ba da mahadi da yawa na babban yuwuwar warkewa.Alpha-amylase, masu hana alpha-glucosidase, da magungunan antioxidant an san su don sarrafa ciwon sukari kuma sun sami kulawa sosai kwanan nan.A cikin binciken da aka gabatar, an zaɓi algae guda huɗu (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, da Cladophora rupestris) don kimanta alpha-amylase, inhibitory alpha-glucosidase, da aikin antioxidant a cikin vitro. .An ƙididdige ayyukan antidiabetic ta yuwuwar hanawa na tsantsa daga alpha-amylase da alpha-glucosidase ta spectrophotometric assays.Ayyukan Antioxidant an ƙaddara ta 2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), da kuma nitric oxide scavenging assay.Gas chromatography-mass spectrometry (GC-MS) an gudanar da bincike don sanin babban fili da ke da alhakin aikin maganin ciwon sukari. Daga cikin nau'o'in abubuwan da aka gano, chloroform tsantsa na C. aerea (IC50 - 408.9 μg / ml) da methanol tsantsa na Chlorodesmis. (IC50 - 147.6 μg / ml) ya nuna tasiri mai tasiri akan alpha-amylase.An kuma kimanta abubuwan da aka cire don hana alpha-glucosidase, kuma ba a sami wani aikin da aka lura ba.Methanol tsantsa na C. rupestris ya nuna sananne free radical scavenging aiki (IC50 - 666.3 μg / ml), sa'an nan H2O2 (34%) da nitric oxide (49%).Bugu da ari, bayanin sinadarai ta GC-MS ya bayyana kasancewar manyan mahaɗan bioactive.Phenol, 2,4-bis (1,1-dimethylethyl) da z, z-6,28-heptatriactontadien-2-daya aka fi samu a cikin methanol tsantsa na C. rupestris da chloroform tsantsa na C. aerea.Sakamakon mu ya nuna. cewa algae da aka zaɓa suna nuna sanannen hanawar alpha-amylase da ayyukan antioxidant.Sabili da haka, halayen mahaɗan masu aiki da ƙididdigar sa a cikin vivo za su zama abin lura.An zaɓi algae guda huɗu don kimanta alpha-amylase, alpha-glucosidase inhibitory, da kuma aikin antioxidant a cikin vitro C. aerea da Chlorodesmis sun nuna gagarumin hanawa ga alpha-amylase, kuma C. rupestris ya nuna sanannen ayyukan scavenging free radicalBabu wani aiki da aka samu akan alpha-glucosidaseGC-MS bincike na abubuwan da ke aiki yana nuna kasancewar manyan mahadi waɗanda ke ba da haske game da aikin antidiabetic da antioxidant na waɗannan algae.Takaitacce da aka yi amfani da su: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.
