An samar da maganin rigakafi na monoclonal (mAb 8281) na musamman don ƙarshen β-galactose (βGal) na glycosphingolipids (GSL) da glycoproteins daga berayen da aka yi musu rigakafi tare da cirewar lipid daga sabbin ƙwayoyin cutar sankarar lymphocytic (ALL).Immuno-bakin ciki Layer chromatography (ITLC) da ƙididdigar gasa tare da ƙa'idodin GSL mai tsafta, sukari kyauta, da neoglycoproteins na roba sun nuna mAb 8281 don zama mai ƙarfi tare da LacCer, GalCer da Gal-β-O- (CH3) 2S (CH3) 2- CONH- (Gal-β-O-CETE) an haɗa shi da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (BSA).Sikari mai ɗorewa kuma ya taka rawa wajen ɗaurewa.Maganin rigakafin ba ya aiki tare da carbohydrates tare da tsarin αGal na ƙarshe da ƙungiyoyin ƙarshe marasa alaƙa.Immunoperoxidase tabo da kuma kwarara cytometry tare da mAb 8281 ya nuna ingantaccen tabo akan kyallen takarda da yawa, gami da tsoka mai santsi, mucosa na ciki, ƙwayoyin lymph node B da monocytes.Binciken ITLC na abubuwan GSL na sabbin ƙwayoyin neoplasms B ta amfani da mAb 8281 ya tabbatar da kasancewar lactosylceramide da galactosylceramide a cikin neoplasms na matakai daban-daban na bambancewa.Saboda ƙayyadaddun sa don ragowar carbohydrate na βGal na ƙarshe, mAb 8281 na iya zama da amfani a cikin tsari da nazarin aikin GSL.
