Kayayyaki

Citicoline (CDP-choline) shine mabuɗin tsaka-tsaki a cikin biosynthesis na phosphatidylcholine, wani muhimmin sashi na membrane na jijiyoyi.An nuna shi don samar da tasiri mai amfani a cikin nau'in dabba da kuma marasa gwajin bugun jini na Amurka.Wannan binciken ya ƙunshi bazuwar (3 allurai na citicoline zuwa 1 placebo), sarrafa abin hawa, gwajin makafi biyu a cibiyoyin Amurka 21.Za a fara magani a cikin sa'o'i 24 na bugun jini kuma ana ci gaba da yin baki har tsawon makonni 6.Ƙimar sakamako na ƙarshe ya kasance a makonni 12.An shigar da marasa lafiya ɗari biyu da hamsin da tara, tare da kusan 65 a cikin kowane rukuni huɗu.Matsakaicin lokaci daga bugun jini zuwa jiyya shine sa'o'i 14.5, kuma babu wani bambance-bambance masu mahimmanci a cikin halaye na asali tsakanin ƙungiyoyi huɗu sai dai nauyin haƙuri.Bambanci mai mahimmanci tsakanin ƙungiyoyi, fifita maganin citicoline, an gani dangane da sakamakon aiki kamar yadda aka auna ta hanyar Barthel Index da Rankin sikelin, ƙididdigar neurologic kamar yadda aka auna ta Cibiyar Nazarin Lafiya ta Kasa (NIH), da kuma aikin fahimi kamar yadda aka auna ta. jarrabawar Mini Mental Status.Lokacin da aka yi amfani da ma'aunin bugun jini na NIH a matsayin mai haɗin gwiwa, duka ƙungiyar citicoline na 500-mg da ƙungiyar citicoline na 2,000-mg sun sami ci gaba mai mahimmanci dangane da kashi dari na marasa lafiya waɗanda ke da sakamako mai kyau akan Barthel Index a 90 days.Babu wasu munanan al'amura ko mutuwa masu alaƙa da ƙwayoyi a cikin wannan binciken.Wannan binciken ya nuna cewa ana iya amfani da citicoline na baka lafiya tare da ƙarancin illa a cikin maganin bugun jini mai tsanani.Citicoline ya bayyana don inganta sakamako na aiki kuma yana rage rashi na neurologic tare da 500 MG na citicoline yana bayyana shine mafi kyawun kashi.