Kayayyaki

Magungunan antineoplastic Fluorouracil sune magungunan fluorouracil.Thymidine phosphorylase da ke cikin ƙwayar ƙwayar cuta yana aiki da shi don canza shi zuwa littafin fluorochemical uracil a cikin ƙari, ta haka yana haifar da sakamako na anti-tumor.Ƙayyadaddun ƙayyadaddun ƙwayar ƙwayar cuta yana da ƙarfi, kuma yawan guba yana da ƙasa.A asibiti amfani da ciwon daji na ciki, colorectal cancer, nono, yawan remission zai iya kai fiye da 30%.

Har yanzu ba a fayyace ingancin aikin chemotherapy don yada cutar kansar ciki ba.An yi la'akari da ingancin paclitaxel na mako-mako tare da doxifluridine (5'-DFUR) a cikin marasa lafiya na ciwon daji tare da m ascites.Maganin ya ƙunshi paclitaxel a cikin jini (iv) wanda aka gudanar a 80 mg / m (2) a kan kwanaki 1, 8 da 15 kowane mako 4, da kuma doxifluridine da aka ba da baki a 533 mg / m (2) a ranakun 1-5 kowane mako.An ƙaddara ƙimar amsa ga marasa lafiya tare da ascites bisa ga Tsarin Jafananci na Gastric Carcinoma.Har ila yau, an auna ma'auni na paclitaxel a cikin ascites. An bincika marasa lafiya ashirin da hudu.Matsakaicin amsa (RR) shine 41.7%, gami da cikakkiyar gafara (CR) da remission na juzu'i (PR) a cikin marasa lafiya 4 da 6, bi da bi.An kiyaye ƙaddamarwar paclitaxel a cikin ascites tsakanin 0.01 μM da 0.05 μM har zuwa 72 hours.Tsakanin rayuwa gabaɗaya (OS) ya kasance kwanaki 215, kuma adadin rayuwa na shekara 1 ya kasance 29.2%.Ba a lura da mummunar guba mai tsanani ba.Paclitaxel na mako-mako a hade tare da doxifluridine yana da tasiri ga masu ciwon daji na ciki tare da m ascites tare da bayanan guba mai karɓa.