Kayayyaki

1.Yawan kamuwa da cututtuka na Staphylococcus aureus da al'umma suka samu na methicillin yana ƙaruwa cikin sauri.Magani mai inganci a tarihi ya haɗa da ɓata lokaci da kuma sarrafa maganin rigakafi.An ƙera wannan binciken ne don sanin ingancin aikin jiyya a cikin maganin cututtukan hannu. An gudanar da gwajin bazuwar a wani asibiti na matakin I County.Marasa lafiya da ke da kamuwa da cuta ta hannu sun sami ko dai vancomycin na ciki na empiric a lokacin shiga ko cefazolin na cikin jijiya.An bi diddigin sakamakon ta amfani da tsananin kamuwa da cuta, amsawar asibiti da ta dace, da tsawon zama.An ƙididdige ƙimar ƙima ta amfani da jimlar farashi ga kowane mai haƙuri a cikin ƙungiyoyin biyu.An yi nazarin ƙididdigar ƙididdiga. An shigar da marasa lafiya arba'in da shida a cikin binciken.An bazu 24 zuwa cefazolin (kashi 52.2) da 22 (kashi 47.8) zuwa vancomycin.Babu wani bambanci na ƙididdiga tsakanin farashin magani (p <0.20) ko ma'anar tsawon zama (p <0.18) betw een ƙungiyoyin.Marasa lafiya da aka bazu zuwa cefazolin suna da ƙimar ƙimar magani mafi girma idan aka kwatanta da marasa lafiya waɗanda aka bazu zuwa vancomycin (p <0.05).Marasa lafiya da ke da cututtukan cututtuka sun fi tsada tsadar magani (p <0.0001) da tsayin tsayin tsayi (p = 0.0002).A kusa da ƙarshen binciken, an gano cewa al'umma sun sami S. aureus da ke da maganin methicillin a asibitin mawallafa ya kai kashi 72 cikin 100, wanda ya sa hukumar nazarin cibiyoyi ta dakatar da binciken da wuri saboda yawan abin da ya faru. Hana kara bazuwar.Maganin da ya dace da wuri don S. aureus mai jure wa methicillin ba a tabbatar da shi ba.Babu bambanci a cikin sakamako ta amfani da cefazolin da vancomycin azaman wakili na farko da aka gano.

2. Tare da ingantawa a cikin warkar da rauni ta hanyar amfani da maganin rigakafi na rigakafi na ciki da kuma gyaran fasaha, cututtuka na gwiwar hannu bayan tiyata sun zama marasa amfani amma har yanzu suna faruwa a wasu tiyata na zaɓaɓɓen gwiwar hannu.Makasudin wannan binciken shine don kimanta aminci da ingancin aikace-aikacen prophylactic na vancomycin a cikin wurin aiki don rage yawan kamuwa da cuta bayan buɗewar gwiwar hannu mai taurin kai.Bita na baya-bayan nan game da irin waɗannan marasa lafiya 272 a cikin shekaru 4. an yi lokaci.A cikin ƙungiyar kulawa (93 marasa lafiya), an yi prophylaxis mai sauƙi tare da daidaitattun maganin rigakafi na ciki;a cikin ƙungiyar vancomycin (179 marasa lafiya), an yi amfani da foda na vancomycin kai tsaye a cikin rauni kafin a rufe tare da daidaitattun ƙwayoyin cuta. tazara: 2.40% -13.52%) idan aka kwatanta da babu (0%; tazarar amincewa: 0-2%04%) a cikin rukunin vancom ycin, wanda ya kasance babban bambanci mai mahimmanci (P = .0027).Babu wani sakamako mara kyau da aka rubuta daga yin amfani da foda na vancomycin kai tsaye. Aikace-aikacen gida na vancomycin foda na iya zama wata hanya mai ban sha'awa don hana cututtuka na gwiwar hannu bayan an saki gwiwar hannu a cikin marasa lafiya tare da ciwon gwiwa na post-traumatic.